Hydroxyl carthamus tinctorius yellow colour A, preparation method and application thereof
A technology of hydroxysafflower and yellow pigment, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of unfavorable large-scale production, small yield, and no practical application value, etc., and achieve shortening Production cycle, improved purity, easy-to-handle effects
Active Publication Date: 2010-08-18
山西德元堂药业有限公司
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Problems solved by technology
Such a small yield is not conducive to large-scale industrial production and has no practical application value
Visible, still do not have the preparation method based on the higher hydroxysafflower yellow A of yield at present, and can guarantee the higher purity of the prepared hydroxysafflower yellow A at the same time
Method used
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preparation Embodiment 2
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The invention relates to a hydroxysaffloryellow A extracted from Chinese medicinal material safflower, a relative preparation method and application thereof. The inventive extraction method of hydroxysaffloryellow A is stuffed into chromatography column according to different diameter-height ratios, the invention uses the upper sample to process column chromatography according to different ratiosbetween upper sample volumes and bed volumes, to separate and purify safflower extract. The invention has simple process, few steps, low cost, high yield, no environment pollution and suitability forindustrialized and large-scale production. The yield of extracted hydroxysaffloryellow A is higher than 50%, while the hydroxysaffloryellow A content tested by high-effect liquid hydroxysaffloryellowA reaches 99.5%. The drug prepared from the hydroxysaffloryellow A can effectively prevent and treat cerebrovascular diseases as cerebral infraction and hypertensive cerebral hemorrhage or the like.
Description
technical field The invention relates to hydroxysafflower yellow A extracted from traditional Chinese medicine safflower, its preparation method and application. Background technique Safflower is the dried flower of Carthamus tinctorius L., a plant in the Compositae family. It has a pungent and warm nature, enters the heart and liver meridians, and has the effect of removing blood stasis and relieving pain. It is the king drug of various prescriptions for promoting blood circulation and removing blood stasis. The extraction of active ingredients in safflower has attracted more and more attention from relevant people. Previous studies have shown that the active ingredients of safflower for promoting blood circulation are mainly concentrated in water-soluble safflower yellow pigment. Safflower yellow is a chalcone compound, which has various pharmacological effects such as expanding coronary artery, anti-oxidation, protecting myocardium, lowering blood pressure, immunosuppress...
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IPC IPC(8): C07H15/20A61K31/7034A61K36/286A61P9/00
Inventor 杨炜
Owner 山西德元堂药业有限公司