Bone repairing material with marine organism as rough material and preparation technique thereof

Abstract

The invention relates to a bone repair material which takes marine organisms as the raw materials and the preparation process. The invention provides a bone filling and repair material, and is characterized in that the bone filling and repair material contains the effective ingredients with the following weight mixing ratio: oyster shell powder: excipient is equal to 1 to 5: 1. The invention further provides the preparation method of the bone filling and repair material. The bone repair material which takes the marine organisms as the raw materials and is provided by the invention can be made into irregular shape, so the invention can meet the bone defects which have the different shapes and need to be filled.

Description

technical field [0001] The invention relates to a bone repair material using marine organisms as raw materials and a preparation process thereof. Background technique [0002] Bone transplantation ranks second in the organ transplantation performed throughout the year in the world; the recognized ideal bone repair material should have good biocompatibility, good osteoinductivity, good osteoconductivity, suitable degradation speed, consistent mechanical The advantages of activity and appearance. [0003] The existing clinical bone filling repair materials include natural materials, artificial synthetic materials, and composite materials; artificial synthetic materials have a complex synthesis process, a single component, and high cost of use; The range of application is narrow; the source of natural materials is single, the manufacturing process is simple, and the price is low, which is a kind of promising bone filling and repairing scaffold material; It is difficult to obt...

AI Technical Summary

Problems solved by technology

[0003] The existing clinical bone filling repair materials include natural materials, artificial synthetic materials, and composite materials; artificial synthetic materials have a complex synthesis process, a single component, and high cost of use; The scope of use is narrow; the source of natural materials is single, the manufacturing process is simple, and the price is low. It is a kind of promising scaffold material for bone filling and repairing; It is difficult to obtain materials and the source is limited; allogeneic bone and heterogeneous bone have the possibility of spreading diseases, which limits its clinical application; collagen has the disadvantages of rapid degradation and low mechanical strength, which is difficult to meet the requirements of bone defect replacement; Similar microporous structure, good tissue compatibility and biodegradability, but a prominent problem in application is still too fast degradation. In the case of incomplete bone formation at 8 weeks, the coral is completely absorbed and loses the role of mechanical support.