Application of indole-2, 3-diketone in preparing antimycotics medicament

Abstract

The present invention relates to an application of indole-2, 3-dione for preparing for an antifungal drug. The indole-2, 3-dione is natural product or manual synthetical product with low toxicity, little side effect and good antifungal effect.

Description

technical field [0001] The invention relates to the application of indole-2, 3-dione (MW147, indole-2, 3-dione) in the preparation of antifungal drugs. Background technique [0002] At present, the extensive application and abuse of broad-spectrum antibiotics, immunosuppressants and glucocorticoids, especially in the case of frequent occurrence of epidemic diseases such as influenza, AIDS, SARS, bird flu, etc., the patient's immunity is reduced, leading to fungal infections rate increases year by year. Moreover, there are adverse factors such as low specificity, high toxicity, and easy drug resistance of antifungal drugs, which not only reduce the quality of life of patients, but also waste a lot of manpower and financial resources. Although western antifungal drugs have remarkable effects, most of them are expensive and highly toxic. Therefore, finding natural antifungal drugs with broad spectrum and low toxic and side effects from traditional plants and marine substances ...

AI Technical Summary

Problems solved by technology

Moreover, there are adverse factors such as low specificity, high toxicity, and easy drug resistance of existing antifungal drugs, which not only reduces the quality of life of patients, but also wastes a lot of manpower and financial resources.

Although the effect of western antifungal drugs is remarkable, most of them are expensive and highly toxic. Therefore, finding natural antifungal drugs with broad spectrum and less toxic and side effects in traditional plants and marine substances is the common focus of medical workers.

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