Preparing method of hypericum perforatum extract

Abstract

The invention relates to a preparation method of Hypericum Perforatum P.E, which is that extraction solvent containing effective components of hypericin and pseudohypericin is obtained by alcohol leaching extraction after the hypericum perforatum raw material is pretreated by immersing in water; then after the steps of heating, distilling, concentrating and extracting, the extract rich in effective components is obtained. The invention can be directly used in dry preparation of extract powder, can also be further separated to prepare hypericin and pseudohypericin with high purity.

Description

technical field [0001] The invention relates to a preparation method of an extract of Hypericum perforatum, which is to obtain an extraction solvent containing active ingredients of hypericin and pseudohypericin after pretreatment of Hypericum perforatum raw material by means of water immersion and extraction by alcohol leaching , Concentrating the extraction solvent by heating and distilling to obtain an extract rich in active ingredients, which can be used for direct drying to prepare extract extract powder, and can also be further separated and prepared for high-purity hypericin and pseudo-hypericin. Background technique [0002] Hypericum perforatum is Hypericum perforatum L. Also known as Melaleuca, St. John's wort St.John'swort, it belongs to the perennial herb of the genus Hypericum in the family Garcinia, with many glandular points on the flowers and leaves, containing a variety of pharmacological effects The ingredients of Ginkgo biloba are one of the best-selling h...

AI Technical Summary

Problems solved by technology

Extraction and processing according to the existing literature report method is difficult to meet the international standard. If the processing method of the international standard extract is used to extract the upper 20cm of Hypericum perforatum in full flowering stage as raw material, the raw material is not only difficult to pick but also difficult to produce. Causes a great waste of resources; if macroporous adsorption resin or solvents are used for refining and separation, although a higher content of active ingredient extract can be obtained, the cost is too high, and its production cost as a common extract dry powder is difficult to be accepted by the market. accept

It is also reported that Hypericum perforatum is treated with alkaline water and then extracted. It has been tested that most or all of the pseudo-hypericin in the extract is destroyed, which does not meet the international standard.