Preparing method of hypericum perforatum extract

A technology of Hypericum perforatum and extract, applied in the field of preparation of Hypericum perforatum extract, can solve the problems of pseudohypericin destruction, high cost, non-compliance with international standards and the like

Inactive Publication Date: 2008-07-23
周佳 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Extraction and processing according to the existing literature report method is difficult to meet the international standard. If the processing method of the international standard extract is used to extract the upper 20cm of Hypericum perforatum in full flowering stage as raw material, the raw material is not only difficult to pick but also difficult to produce. Causes a great waste of resources; if macroporous adsorption resin or solvents are used ...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] 100 grams of Hypericum perforatum raw materials are pulverized, then add 300ml of water, soak at room temperature for 2 hours, remove the water soaking solution, and use 300ml, 200ml, and 200ml of 80% ethanol solvent to reflux the raw materials after water pretreatment for three times. After filtration, they were combined and concentrated under reduced pressure, and the concentrated extract was vacuum-dried to obtain 12 grams of Hypericum perforatum extract dry powder with a UV detection content of 0.42%.

Embodiment 2

[0020] 200 grams of Hypericum perforatum raw materials are pulverized, then add 600ml of water, soak for 15 minutes under heating and boiling, remove the water soaking solution, and use 300ml, 200ml, and 200ml of 40% ethanol solvent to extract the raw materials after water pretreatment in three reflux, After the extracts were filtered, they were combined and concentrated under reduced pressure, and the concentrated extract was vacuum-dried to obtain 29 grams of Hypericum perforatum extract dry powder with a UV detection content of 0.32%.

Embodiment 3

[0022] 500 grams of Hypericum perforatum raw materials are pulverized, then add 1300ml of water, soak at room temperature for 2.5 hours, remove the water soaking solution, and use 1500ml, 1300ml, 1000ml of 85% ethanol solvent to reflux the raw materials after water pretreatment for three times. After filtering, they were combined and concentrated under reduced pressure, and the concentrated extract was vacuum-dried to obtain 64.6 grams of Hypericum perforatum extract dry powder with a UV detection content of 0.38%.

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Abstract

The invention relates to a preparation method of Hypericum Perforatum P.E, which is that extraction solvent containing effective components of hypericin and pseudohypericin is obtained by alcohol leaching extraction after the hypericum perforatum raw material is pretreated by immersing in water; then after the steps of heating, distilling, concentrating and extracting, the extract rich in effective components is obtained. The invention can be directly used in dry preparation of extract powder, can also be further separated to prepare hypericin and pseudohypericin with high purity.

Description

technical field [0001] The invention relates to a preparation method of an extract of Hypericum perforatum, which is to obtain an extraction solvent containing active ingredients of hypericin and pseudohypericin after pretreatment of Hypericum perforatum raw material by means of water immersion and extraction by alcohol leaching , Concentrating the extraction solvent by heating and distilling to obtain an extract rich in active ingredients, which can be used for direct drying to prepare extract extract powder, and can also be further separated and prepared for high-purity hypericin and pseudo-hypericin. Background technique [0002] Hypericum perforatum is Hypericum perforatum L. Also known as Melaleuca, St. John's wort St.John'swort, it belongs to the perennial herb of the genus Hypericum in the family Garcinia, with many glandular points on the flowers and leaves, containing a variety of pharmacological effects The ingredients of Ginkgo biloba are one of the best-selling h...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P25/24A61P31/16A61P35/00
Inventor 周佳代维正
Owner 周佳
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