Method of preparing low molecular active substance pill of holothurian and oyster

An active substance and low molecular technology, applied in the field of preparation of low molecular weight sea cucumber and oyster active substance drop pills, can solve the problems of single preparation technology, easy moisture absorption of contents, trust crisis, etc., and achieves rich nutrition, easy portability and convenience The effect of taking

Active Publication Date: 2008-07-30
YANTAI YUANLIDE MARINE ORGANISM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, health foods prepared from sea cucumbers or oysters are mostly in the form of hard capsules, soft capsules, and oral liquids. The above three forms are not suitable for marine organisms such as sea cucumbers and oysters, except for the single preparation technology. Many deficiencies, such as: 1. At present, neither the physical method nor the enzymatic hydrolysis method has any technical advantages in molecular weight control, which affects the efficacy and absorption; 2. Due to the problem of the preparation form, the content is very easy to absorb moisture and lack Stability for a long time; 3. In the market, due to people's doubts about the contents of the current dosage form health care products, there is a crisis of confidence, which greatly limits product development and utilization

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1, a kind of preparation method of low-molecular-weight sea cucumber, oyster active substance dripping pill, is to carry out longitudinal dissection to fresh sea cucumber to remove internal organs and intracavity sundries, wash, drain, beat into original pulp by colloid mill, the above work The temperature is required to be completed below 25°C. Stir the sea cucumber puree evenly in the reactor and adjust its pH value between 6-7.5. Add 0.5-1‰ compound animal protease at a constant temperature of 40-60°C, and the enzymatic hydrolysis time 1-3 hours, then heat up to 70-95°C for enzyme inactivation, centrifuge to take the supernatant and adjust the pH value between 5.5-7.5, then add 0.2-1‰ compound at a temperature of 40-60°C Flavored protease, heat up to 70-95°C after 2 hours to inactivate the enzyme, after cooling, centrifuge to take the supernatant, pass the supernatant through G25 gel column chromatography to remove part of the salt and collect the active co...

Embodiment 2

[0013] Embodiment 2, a kind of preparation method of low-molecular sea cucumber, oyster active substance dripping pill, is on the basis of embodiment 1, and present embodiment adopts polyethylene glycol 4000, polyoxyethylene stearate, stearic acid to mix, The condensing agent adopts camellia oil and liquid edible wax to mix, and others are identical with embodiment 1.

Embodiment 3

[0014] Embodiment 3, a kind of preparation method of low-molecular weight sea cucumber, oyster active substance drop pill, is on the basis of embodiment 1, and present embodiment adopts glycerin, gelatin, poloxamer, glyceryl monostearate, beeswax to mix , condensing agent adopts simethicone oil, camellia oil, liquid cooking wax to mix, and others are exactly the same as embodiment 1.

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PUM

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Abstract

The invention discloses a preparation method of a low molecular dropping pill with sea cucumber and oyster active materials; the invention is characterized by taking the sea cucumber or the oyster meat as the raw material, adopting the biological enzymolysis method, obtaining the sea cucumber enzymolysis liquid or the oyster enzymolysis liquid, correcting the flavor by the compound flavor protease, getting the low-molecular-weight active component liquid after ultrafiltrating the liquid after enzyme inactivation, adding an edible dropping pill matrix and getting the low molecular sea cucumber and the oyster active material dropping pill. The invention is made from the low-molecular active material and the utilization ratio of the active material is high. The low molecular sea cucumber and the oyster active material dropping pill is easy to be absorbed by the human body, rich in nutrient, reasonable in formulation and easy in administration.

Description

1. Technical field [0001] The invention belongs to the technical field of marine biological health care products, and in particular relates to a preparation method of low molecular weight sea cucumber and oyster active substance drop pills. 2. Background technology [0002] At present, health foods prepared from sea cucumbers or oysters are mostly in the form of hard capsules, soft capsules, and oral liquids. The above three forms are not suitable for marine organisms such as sea cucumbers and oysters, except for the single preparation technology. Many deficiencies, such as: 1. At present, neither the physical method nor the enzymatic hydrolysis method has any technical advantages in molecular weight control, which affects the efficacy and absorption; 2. Due to the problem of the preparation form, the content is very easy to absorb moisture and lack Long-term stability; 3. In the market, due to people's doubts about the contents of the current dosage form health care product...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/325A23L1/33A23L1/333A23L1/03A23L1/29A61K35/56A61K9/20A61P3/02A23L17/00A23L17/40A23L17/50A23L29/00A23L33/00A61K35/616A61K35/618
Inventor 沈炳鑫王伟成
Owner YANTAI YUANLIDE MARINE ORGANISM CO LTD
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