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Silk screen printing method for producing blood sugar test paper

A technology of screen printing and blood glucose test strips, which is applied in the field of biosensing, can solve the problems of complex manufacturing process and unfavorable industrial scale production of products, and achieve the advantages of convenient post-processing and packaging, simplified production equipment, and guaranteed accuracy and repeatability Effect

Inactive Publication Date: 2008-08-20
胡军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in addition to the multi-layer screen printing technology, this method also needs to use biological element spotting equipment to coat the biological enzyme solution on the surface of the electrode, which makes the manufacturing process complicated and is not conducive to the industrial scale production of products.

Method used

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  • Silk screen printing method for producing blood sugar test paper

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: Polyethylene (PVC) boards are pre-cut into 21×9 cm substrates for later use.

[0020] (1) Add 1.2% hydroxyethyl cellulose and 10% benzoquinone, an electronically conductive carrier material, to 1 gram of silk-screen conductive carbon ink (Acheson 423SS), mix well and set aside.

[0021] (2) Fix the 280-mesh metal or nylon polyester material screen on the square light metal frame, apply Kodak photosensitive glue in the dark room, and dry it for later use.

[0022] (3) Place the computer-drawn negatives of the working electrode and the reference electrode on the photosensitive adhesive, and expose them to a 20-watt ultraviolet lamp for 15 minutes. Rinse off the unhardened photosensitive adhesive covered by the electrode negative with a high-pressure water gun. After drying, a screen printing template is formed.

[0023] (4) Install the screen printing template with the working electrode and reference electrode graphics on the (DEK-245) automatic screen pri...

Embodiment 2

[0028] Embodiment 2: polyester (PET) sheet material, cut into 21 * 9 centimeter substrates in advance for future use.

[0029] (1) Add 1.8% hydroxyethyl cellulose and 15% benzoquinone, an electronically conductive carrier material, to the silk-screen conductive carbon ink (Acheson423 SS). After mixing, set aside in the refrigerator at 4°C for later use.

[0030] (2) Fix the 300-mesh metal or nylon polyester wire mesh on a square light metal frame, apply Kodak photosensitive glue in the dark room, and dry it for later use.

[0031] (3) Place the computer-drawn negatives of the working electrode and the reference electrode on the photosensitive adhesive, and expose them to light for 25 minutes under a 20-watt ultraviolet lamp. Rinse off the unhardened photosensitive adhesive covered by the electrode negative with a high-pressure water gun. After drying, a screen printing template is formed.

[0032] (4) Install the screen printing template with the working electrode and refer...

Embodiment 3

[0035] Embodiment 3: Polyphenol ester (PP) boards, which are pre-cut into 21×9 cm substrates for later use.

[0036] (1) Add 2.5% hydroxyethyl cellulose to the conductive carbon ink for silk screen printing, add 20% potassium ferricyanide, an electronically conductive carrier material, and mix for subsequent use;

[0037] (2) Fix the 350-mesh metal or nylon polyester material screen on the square light metal frame, apply Kodak photosensitive glue in the dark room, and dry it for later use;

[0038] (3) Place the working electrode and the reference electrode negative film drawn by the computer on the photosensitive glue, expose to light for 30 minutes under a 40-watt ultraviolet lamp, rinse off the unhardened photosensitive glue covered by the electrode negative film with a high-pressure water gun, and form a silk screen template after drying;

[0039] (4) Install the screen printing template with working electrode and reference electrode graphics on the automatic screen printi...

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Abstract

The invention provides a blood glucose testing instrument and the producing method thereof, which belongs to the field of bio-sensor technology. The substrate of the testing paper is printed with working electrode, reference electrode and electrical circuit which are formed by carbon-coating, one end of the substrate is printed with wire connected with readout instrument, the working electrode and reference electrode are respectively printed on carbon-coating above substrate conductive silver layer, the working electrode is also printed with enzyme, medium and adhesive. According to bio-sensor and electrochemical principle, the testing paper is made through silk-screen process, not only conductive circuit is printed, but also sensitive bio-element is directly printed on electrode supporter, the print amount of the print material and print area are totally and exactly controlled by computer. Once the testing paper contacts human body fluid, the testing result can be easily and directly read out on corresponding matching instrument, the producing method is easy, and has high precision, low cost, which is convenient for later process and encapsulation, and is good for large-scale production.

Description

technical field [0001] The invention relates to a test paper and a screen printing production method thereof, in particular to a test paper matched with a blood sugar tester and a screen printing production method thereof, belonging to the technical field of biosensing. Background technique [0002] According to statistics, there are more than 45 million diabetic patients in my country, and the number is increasing at a rate of 1.5% every year. One of the effective means to control the development of diabetes is to implement blood sugar testing every day to strictly control medication and diet, and maintain the stability of the patient's blood sugar index. Some blood glucose meters currently on the market use general silk screen printing technology for supporting test strips. The production process of this kind of blood glucose test strips is simple and rough. Higher, it can only reach pilot-scale production, and it is difficult to implement large-scale industrialized conti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/66G01N33/52G01N27/406H05K3/46
Inventor 胡军
Owner 胡军
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