Partition type tissue engineering spinal cord

Abstract

The invention discloses a zoning tissue engineering spinal cord which comprises a spinal external catheter and a central catheter. A gray matter catheter which is provided with the same shape as spinal gray matter is arranged in the spinal external catheter. Corresponding catheters are respectively arranged in a white matter region according to the geometric shapes of uplink fiber bundles and downlink fiber bundles. The zoning tissue engineering spinal cord can play the role of correct guidance and lead to the result that the spinal gray matter, white matter and the uplink fiber bundles and the downlink fiber bundles in the white matter respectively grow in different regions.

Description

Technical field: [0001] The invention relates to an artificial spinal cord. Background technique: [0002] With the process of social modernization and the acceleration of people's life rhythm, there will inevitably be more traffic accidents, high-altitude falls, sports accidents and other incidents. At the same time, frequent local wars, violent incidents and natural disasters such as earthquakes will cause spinal cord injuries. (spinal cord injury, SCI) patients are increasing. Although there is no accurate data on the incidence of SCI in various countries, it is generally estimated at 20-60 people / 1 million people / year. SCI is an injury to the central nervous system with a high morbidity rate and serious consequences. The injury site mostly occurs in the spinal cord of the cervical and lumbar segments, which will cause loss of motor and sensory functions below the level of injury, and at the same time bring chronic pain. even mental disorders. Due to the high incidence...

AI Technical Summary

Problems solved by technology

Therefore, in such a scaffold material, even if the ascending and descending fiber bundles located in the peripheral white matter of the spinal cord are regenerated, they can only grow in mismatched or even misplaced channels or micropores, resulting in that the regenerated nerve fibers cannot be regularly distributed in the corresponding channels. The growth and extension of the region can only grow in a disorderly and disorderly manner, which eventually leads to the intertwining of the upper and lower regenerative fibers and affects the extension of other fibers or the migration of neurons, greatly reducing the repair effect

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