Vitamin C clean production method

Abstract

The invention discloses a cleaner production method of Vitamin C. In the method, the steps of converting sodium gulonic acid into gulonic acid are as follows: a. strong acid is added into sodium gulonic acid solution and then the pH of the solution is regulated to be 3.0 to 4.5; b. the solution film with the regulated pH is ultrafiltered; c. the strong acid is added into the ultrafiltered solution so as to regulate the pH to be 1.6 to 1.7; d. the solution with regulated pH in step c is subjected to concentration, crystallization and centrifugation so as to prepare mixed dry products; e. the mixed dry products are dissolved in methanol and then filtered so as to prepare the methanol solution of the gulonic acid. The production method of the invention has the advantages that a large amount of water, caustic soda liquid and hydrochloric acids are saved, and basically no sewage is discharged in the process of conversion, thereby solving the problem of environmental contamination, and meeting the discharge standard prescribed by the state. The production method has basically no loss on yield in the process of conversion, thereby greatly reducing investment and production costs.

Description

technical field

[0001] The invention relates to the field of pharmaceutical production, in particular to a clean production method of vitamin C. Background technique

[0002] At present, vitamin C (Vc) production enterprises generally adopt the ion exchange method to transform the sodium gulonic acid solution into the gulong acid solution, then concentrate, crystallize, and centrifuge to obtain the dry product of the gulong acid, and then put the dry product of the gulong acid into a certain amount of methanol Carry out esterification conversion in the middle, and finally make Vc-Na or Vc. In the transformation method, gulonate crystals are prepared by going through a cation exchange step from a gulonate sodium solution. In this step, after the cation exchange resin is saturated, it needs to be backwashed with a large amount of tap water, then regenerated by adding 4% liquid caustic soda for 2 hours, then washed with tap water until the pH is 8, and regenerated by adding 7-...