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Pregnancy-assisting formulation for treating infertility induced by dysfunctional ovulation and its preparation method

A technology for dysfunction and infertility, which is applied in the field of infertility preparations and preparations, can solve the problems of insignificant effect, weak pertinence, and few varieties, and achieves good safety, convenient operation, and helpfulness. effect on absorption

Inactive Publication Date: 2011-02-02
天津曹开镛中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are very few Chinese patent medicines clinically used to treat infertility, and they are not highly targeted, so the effect on the treatment of infertility caused by ovulatory dysfunction is not obvious.

Method used

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  • Pregnancy-assisting formulation for treating infertility induced by dysfunctional ovulation and its preparation method
  • Pregnancy-assisting formulation for treating infertility induced by dysfunctional ovulation and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The assisted-fertility preparation for treating infertility caused by ovulatory dysfunction in this embodiment is mainly made of the following pharmaceutical raw materials in amounts by weight:

[0018] Epimedium (made) 200 Cuscuta 200 Antler glue 30

[0019] Angelica 100 Astragalus 200 Paeoniae Alba 100

[0020] Rehmannia glutinosa 100 Amomum 100 Scutellaria baicalensis 80

[0021] Cyperus (made) 150 Notopterygium 80

[0022] Preparation:

[0023] a. Weigh the above-mentioned medicinal raw materials according to the proportioning ratio, then mix the ten medicinal raw materials except the antler gum, add water and decoct twice, each time for 2 hours, combine the filtrate, filter, and concentrate to a thick paste;

[0024] b. Add deer horn gum to the above-mentioned thick ointment, and then make oral solid preparation and oral liquid preparation according to conventional pharmaceutical technology and add corresponding commonly used pharmaceutical excipients.

Embodiment 2

[0026] The assisted-fertility preparation for treating infertility caused by ovulatory dysfunction in this embodiment is mainly made of the following pharmaceutical raw materials in amounts by weight:

[0027] Epimedium (made) 110 Cuscuta 160 Antler glue 25

[0028] Angelica 80 Astragalus 135 Paeoniae Alba 75

[0029] Rehmannia 60 Amomum 50 Scutellaria baicalensis 50

[0030] Rhizoma Cyperus (made) 100 Notopterygium 60

[0031] The preparation method is the same as in Example 1.

Embodiment 3

[0033] The assisted-fertility preparation for treating infertility caused by ovulatory dysfunction in this embodiment is mainly made of the following pharmaceutical raw materials in amounts by weight:

[0034] Epimedium (made) 240 Cuscuta 240 Antler glue 45

[0035] Angelica 125 Astragalus 265 Paeoniae Alba 155

[0036] Rehmannia glutinosa 150 Amomum 145 Scutellaria baicalensis 120

[0037] Cyperus (made) 220 Notopterygium 110

[0038] The preparation method is the same as in Example 1.

[0039] The fertility aid preparation for treating infertility caused by ovulation dysfunction provided by the invention is brown to tan and has a mild taste. In order to verify the therapeutic effect of the assisted pregnancy preparation, the present inventor conducted a systematic clinical observation on 540 patients with infertility caused by ovulatory dysfunction by using capsules belonging to oral solid preparations in the above-mentioned assisted gestational preparation, of which 21- ...

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Abstract

The invention relates to a preparation with effect of assisting pregnancy for treating sterility due to ovulatory dysfunction, and a preparation method thereof. The preparation is prepared from the following materials (by weight part): Herba Epimedii (processed) 110-240, Cuscuta chinensis seed 160-240, Colla cornus cervi 25-45, Angelica sinensis 80-125, Astragalus membranaceus 135-265, Paeonia lactiflora 75-155, Rehmannia glutinosa 60-150, Fructus Amomi 50-145, Scutellaria baicalensis 50-120, Cyperus rotundus (processed) 100-220, and Rhizoma Et Radix Notopterygii 60-110. The effective ingredients of the raw materials in the preparation are extracted by decoction, and activities thereof are remained, so as to remarkably improve the dissolution rate, promote absorption of the effective ingredients, and improve bioavailability. In addition, the preparation is a pure Chinese medicinal preparation, thereby resulting in good safety and no toxic or side effects after long-term administration.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to an auxiliary pregnancy preparation and a preparation method for treating infertility caused by ovulation dysfunction, which are made from traditional Chinese medicine. Background technique [0002] Infertility is a common clinical disease. Women who do not use contraception after marriage, have normal sex life, and live together for 2 years without conceiving are called primary infertility; The disease suffered by those who have not conceived again for 2 consecutive years is called secondary infertility. Abnormal ovulation is one of the main causes of infertility. Congenital ovarian dysplasia, premature ovarian failure, polycystic ovary, etc. will affect the development and discharge of eggs. Currently, there are very few types of Chinese patent medicines clinically used to treat infertility, and their pertinence is not strong, so the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P15/08A61K35/32
Inventor 曹开镛
Owner 天津曹开镛中医医院