Composition of starwort total glycosidoprotein, preparation method and uses thereof
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A riboside protein and composition technology, which is applied in the direction of peptide/protein components, medical preparations containing active ingredients, plant/algae/fungus/moss components, etc., to enhance the antiviral effect and increase the total riboside proteosomes Ingredient content, good effect of antiviral drug application
Inactive Publication Date: 2009-03-18
朱耕新
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[0005] But so far, there is no composition of total riboside proteosome components extracted from chickweed or other plants of the genus Chickweed with a molecular weight distribution of 1,000-100,000 and a dark brown powder as a broad-spectrum antiviral drug Applied coverage
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[0022] One), the preparation method of composition comprises following three kinds:
[0023] 1. Its preparation method 1, the steps include: convert the crude drug or fresh grass of chickweed or other plants of the genus Chickweed into hay, extract it with water to obtain an aqueous solution after precipitation, centrifugation or filtration, and pass through pre-treated The macroporous resin column to absorb the composition of the composition, wash the macroporous resin column with water, then heat the macroporous resin column to 45°C to 55°C, wash the column with hot distilled water of the same temperature and collect the deep Brown distilled water, followed by heating to 45°C-55°C with lower alcohols or acetone with a concentration of 20%-35% to elute from the resin column, and collecting the eluted brown-red or dark brown-red alcohol or acetone After recovering the alcohol or acetone, the solution is combined with the collected dark brown aqueous solution, concentrated unti...
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Abstract
At present, the whole world is a lack of clinically high-efficient and safe broad-spectrum antiviral drugs. A composite of total riboside proteosome component that is prepared from plant chickweed or another stellaria plant and extracted by two resin adsorption methods and a hydroalcohol through a hyperfiltration method, has a molecular weight of 1,000 to 100,000 and is in the form of dark brown powder is used as a safer and more high-efficient broad-spectrum antiviral natural drug. The total protein of the total riboside proteosome component takes up 15% to 25% in the chemical construction, and is made up of 17 amino acids, such as asparaginic acid, glutamic acid, serine, histidine, cystine, methionine, isoleucine and the like in proportions; the proportion of sugar comprises ribose, glucose, galactose and arabinose, and total ribonucleotide takes up 5% to 10% and comprises uracil, thymine, thymidine, guanosine, 2-chloro-adenosine. The composite can be used as a drug for treating virus diseases, such as AIDS virus, hepatitis virus, respiratory syncytial viruses like influenza virus, parainfluenza virus, adenovirus, and the like, including highlypathogenic avian influenza virus, and condyloma virus, enterovirus, mumps virus, herpes simplex virus, herpes zoster virus and varicella-zoster virus. Moreover, the composite has no toxicity, and can be made into more than 10 types of medicine preparations, health products and the like, while causing no environmental pollution in the production process.
Description
1. Technical field: [0001] On the basis of the inventor's publication numbers CN 1377680A and CN 1498630A two invention patents, this invention discloses the progress and results of in-depth research on the chemical components of the composition in the above two patents. A composition of total riboside proteosome components extracted from Chickweed plants with a molecular weight distribution of 1,000-100,000 and a dark brown powder is used as a safer and more efficient broad-spectrum antiviral natural medicine. 2. Background technology: [0002] After searching the United States "Chemical Abstracts" (Chemical Abstracts) from 1920 to Volume 134 in 2001, the chemical constituents of the reported chickweed plants are mainly flavonoids and flavonoid glycosides, saponins and pro-saponins, cyclic amino Acids, ferulic acid and its esters, chlorogenic acid, neochlorogenic acid, caffeic acid, quinic acid, ascorbic acids, oxalic acid and calcium oxalate, monoacylgalactose lipids, alka...
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