Prevention and treatment of otitis media with non-pathogenic bacterial strains

A non-pathogenic, otitis media technology, applied in the field of prevention and treatment of otitis media, capable of solving frequent and other problems

Inactive Publication Date: 2009-06-17
NESTEC SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In fact, antibiotics are prescribed more frequently for otitis media than for any other ailment in infancy

Method used

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  • Prevention and treatment of otitis media with non-pathogenic bacterial strains
  • Prevention and treatment of otitis media with non-pathogenic bacterial strains

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] An example of the composition of the infant formula of the invention is given below. This composition is given by way of illustration only.

[0052]

[0053]

Embodiment 2

[0055] This example compares the inhibitory effect of the composition of the invention against some pathogens commonly associated with otitis media with the inhibitory effect of the components of the composition alone. The bacterial strains tested were L. rhamnosus ATCC 53103 and S. salivarius DSM 13084 alone and in combination. The pathogenic strains were three different strains of Streptococcus pneumoniae and one strain of Alloiococcus otitidis against which bacterial strains were evaluated for their inhibitory activity. Inhibition profiles of test strains were determined by using deferred antagonism as previously described (Tagg and Bannister 1979). Briefly, 1 cm wide diameter streak cultures of test strains were inoculated onto nutritionally appropriate agar. After incubation, slides were used to remove macroscopic bacterial growth, and residual cells on the agar surface were killed by exposure to chloroform vapor for 30 minutes. Allow the agar surface to dry for 30 min....

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PUM

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Abstract

This invention relates to a composition comprising a bacterial strain capable of boosting the systemic immune response, a bacterial strain capable of exerting bacteriostatic effects on pathogens associated with development of otitis media such as Streptococcus pneumoniae, untypeable Haemophilus influenzae and Moraxella catarrhalis and a bacterial strain capable of exerting bacteriocidal effects on such pathogens. The invention further extends to the use of such a composition in the prevention or treatment of otitis media.

Description

technical field [0001] The present invention relates to the prevention and treatment of otitis media, especially in infants and small children. Background technique [0002] Infections of the respiratory tract are very common, especially in infants and young children. For example, babies typically experience three to six of these infections during the first year of life. Such infections can be of bacterial or viral origin. Examples of respiratory viral infections include common cold, influenza and respiratory syncytial virus. Examples of bacterial infections of the respiratory tract include pneumonia and otitis media. [0003] Frequent respiratory infections are often accompanied by acute otitis media. This is a middle ear infection in which the Eustachian tube, which connects the middle ear cavity to the outside environment through the mouth, becomes inflamed and then blocks, trapping bacteria in the middle ear. The middle ear cavity also becomes inflamed and produces ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/74A23C9/12A61P27/16A23L33/00
CPCA23Y2240/75A23V2002/00A61K35/747A23L1/3014A23Y2220/73A23L1/296A61K35/744A23L33/40A23L33/135A61P27/16A23V2200/3202A23V2200/3204A23V2200/324A23V2400/175A23V2400/249
Inventor M-C·菲绍H·布吕索
Owner NESTEC SA
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