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Chinese medicament preparation for treating renal proteinuria and diabetic renal proteinuria and preparation method thereof

A technology for diabetic nephropathy and traditional Chinese medicine preparations, applied in pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., can solve problems such as changes in filtration membrane filtration, renal tubular reabsorption disorders, etc., to improve physical weakness. , Improve renal function, reduce the effect of urinary protein

Inactive Publication Date: 2009-08-05
TIANKE RENXIANG TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Under normal circumstances, due to the filtration of the glomerular filtration membrane and the reabsorption of the renal tubules, the protein content in the urine excreted by healthy people is very small, but when suffering from kidney disease, the filtration of the filtration membrane Altered action, impaired tubular reabsorption

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Take 600g astragalus, 200g cinnamon, 200g aconite (made), 1600g rehmannia glutinosa, 800g dogwood (made), 600g moutan cortex, 800g yam, 600g poria cocos, and 600g Alisma chinensis, and grind them into fine powder, pass through a 100-mesh sieve, mix evenly, and Sterilize by autoclaving at 105°C, add an equal amount of refined honey, mix evenly, make pellets, and pack separately to obtain large honeyed pills.

Embodiment 2

[0033] (1) Take astragalus 600, cinnamon 200, dogwood 800, and yam 800 and grind them into fine powder, pass through a 120-mesh sieve, mix well, and sterilize by autoclaving at 105°C for 2 hours, and set aside;

[0034] (2) Take 200g of aconite (made), 1600g of Rehmannia glutinosa, 600g of Moutan cortex, 600g of Poria cocos, and 600g of Alisma, and grind them into coarse powder, add 10 times the amount of water, decoct for 2 hours, filter the decoction; add 8 times of medicinal residue Measure water, decoct for 1 hour, and filter the decoction; add 8 times the amount of water to the dregs, decoct for 1 hour, filter the decoction, combine, and concentrate the filtrate under reduced pressure at 55°C to a clear liquid with a relative density of 1.20. paste;

[0035] (3) Take the clear ointment obtained in step (2), add the medicinal material fine powder obtained in step (1), mix evenly, dry, pulverize into fine powder, and pass through a 120-mesh sieve;

[0036] (4) Take the fin...

Embodiment 3

[0039] (1) Take astragalus 1200g, cinnamon 400g, aconite (made) 400g, Rehmannia glutinosa 3200g, dogwood (made) 1600g, Moutan bark 1200g, Chinese yam 1600g, Poria cocos 1200g, Alisma 1200g and pulverize into coarse powder, add 12 times the amount of water, Decoct for 2 hours, filter the decoction; add 10 times the amount of water to the dregs, decoct for 1 hour, and filter the decoction; add 8 times the amount of water to the dregs, decoct for 1 hour, combine the decoction, filter, and filtrate Concentrate under reduced pressure at 60°C to a clear paste with a relative density of 1.20, spray dry to obtain extract powder;

[0040] (2) Get 0.6% magnesium stearate and add in the extract powder, mix evenly, pack separately, obtain capsules.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating nephrosis and diabetes nephrosis proteinuria and a preparation method thereof. The preparation is prepared from hoantchy root, cinnamon, acontum fischeri, prepared radix rehmanniae, dogberry, peony bark, yam, tuckahoe and oriental waterplantain rhizome, and can be prepared into pills, granules, tablets, capsules and soft capsules. The preparation has the efficacies of nourishing Qi and raising Yang, reinforcing the spleen and kidney and clearing damp, is mainly used for treating acute and chronic nephritis, nephrosis syndrome, diabetes nephrosis oedema, long-term non-elimination of urine protein, and has definite effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating nephropathy and diabetic nephropathy proteinuria and a preparation method thereof, belonging to the technical field of Chinese patent medicines. Background technique [0002] Proteinuria is a main symptom in acute and chronic glomerulonephritis, nephrotic syndrome, and diabetic nephropathy, and it is a persistent and progressive renal damage. [0003] Under normal circumstances, due to the filtration of the glomerular filtration membrane and the reabsorption of the renal tubules, the protein content in the urine excreted by healthy people is very small, but when suffering from kidney disease, the filtration of the filtration membrane The effect will be changed, and the reabsorption of renal tubules will be impaired. [0004] Proteinuria is the most risk factor for the progression of nephropathy and diabetic nephropathy. Clinically, persistent proteinuria often means subst...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/16A61K9/20A61K9/48A61P3/10A61P13/12
Inventor 王丽娟
Owner TIANKE RENXIANG TECH BEIJING
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