Medicament for repairing mesothelium, endothelium and epidermal tissue, as well as preventing adhesions and obstruction, and preparation method

Abstract

The invention provides a medicament for promoting the repair of mesothelial, endothelial and epithelial tissues and preventing can controlling adhesion and obstruction and a preparation method thereof. The medicament mainly comprises the following components by the proportion: 1 part of allantoin, 0.002 to 0.4 part of glucocorticoid, 0.2 to 10 parts of nitroimidazole derivatives and a proper amount of materials comprising pH regulator, osmotic pressure regulator, excipient, stabilizer and auxiliary materials. The medicament is a medicinal preparation or material applicable to surgery fields, traumas, body surfaces, abdominal membranes, lung membranes, articular cavities, tunica vaginalis, endangium, arachnoid membranes, ventricle, lymphatic vessels, body cavity, alimentary tracts, respiratory tracts, vagina and skins. The invention has the effect of promoting the repair of epithelial tissue structure, is capable of resisting inflammation, exudation and infection, lubricates protective tissues, accelerates the post-operation recovery of intestinal obstruction, controls the adhesion, improves the success rate of operations and reduces sequelae.

Description

1. Technical field: [0001] The invention belongs to the field of medicine and chemical industry, and it is a kind of medicine used in the field of surgery, wound area, body surface, peritoneum, pleura, joint cavity, sheath, vascular intima, arachnoid, ventricle, lymphatic vessel, body cavity, digestive tract, respiratory tract , vaginal and skin preparations or medicinal materials. 2. Technical background: [0002] There are two results of tissue repair: complete repair and incomplete repair. Incomplete repair: Exudation, organization, and transitional hyperplasia and filling of connective tissue after tissue injury, resulting in changes in local tissue structure and morphology, resulting in disordered anatomical layers, resulting in obvious changes in appearance and morphology, accompanied by local functional loss in varying degrees Or completely lost, and even the resulting pathological changes lead to complications. Complete repair: the anatomical level of the repaired ...

AI Technical Summary

Problems solved by technology

[0007] Loose intima, deposition of metabolites and blood components cause atherosclerosis, leading to insufficient blood supply and embolism. At present, all methods of thrombolysis and interventional surgery to implant stents have not yet involved in promoting the recovery of the intima to maintain its original state. complete solution

There is no scientific and effective method to increase the survival rate of skin grafting, eliminate huge scars on the skin, maintain skin compactness, and prevent age spots and pigmentation caused by delaying the deposition of its metabolites.