Thiourea compounds
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- NAT INST OF HEALTH REPRESENTED BY THE SEC OF THE DEPT OF HEALTH & HUMAN SERVICES NAT INST OF HEALTH
- Publication Date
- 2009-09-02
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
[0001] cross reference
[0002] Pursuant to 35 U.S.C. §119(e), this application claims priority to US Provisional Application 60 / 837,782, filed August 15, 2006. The content of this provisional application is hereby incorporated by reference. Background technique
[0003] Hepatitis C virus (HCV) infection is estimated to affect 170 million people worldwide. The disease is mainly spread through contaminated blood products. Although the spread of the disease has slowed due to advances in blood screening mechanisms in many countries, HCV infection remains the leading cause of death from liver-related disease worldwide. For example, approximately 10,000 people die each year from hepatitis C virus infection in the United States alone. Due to the lack of effective treatment, this mortality rate is projected to more than triple in the ensuing two decades.
[0004] At present, the success rate of treatment with interferon alpha is not high, especially for genotype-I infections that...