Artificial saliva

Abstract

The invention relates to artificial saliva, which comprises a plurality of inorganic salt, HPMC, a preservative, a flavoring agent and other components. The artificial saliva has the following advantages that: (1) the artificial saliva can rapidly improve symptoms of a patient suffering from xerostomia, and can maintain the function in a longer period; (2) the artificial saliva has good stability; and (3) the artificial saliva has a good mouthfeel when in use.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to artificial saliva for preventing and treating xerostomia and improving xerostomia and related symptoms. technical background [0002] Sjogren's syndrome is an autoimmune disease characterized by high lymphocyte infiltration of exocrine glands. The most common symptom is dry mouth and eyes, but its clinical manifestations are far from limited to this, but a systemic disease. It may be involved, and kidney involvement is very common. Sjögren's syndrome occurs the most in autoimmune rheumatic diseases, and malignant lymphoproliferation is another feature. It is a chronic immune disease. There are two types of it: primary and secondary, with a prevalence rate of 0.29% to 0.77%, mostly after middle age, with a high incidence between 45 and 55 years old, and 90% of them are women. Xerostomia is one of the important components of Sjogren's syndrome. [0003] The ...

AI Technical Summary

Problems solved by technology

The lack of saliva in patients with xerostomia will cause strong discomfort of dry mouth, and at the same time, it is easy to cause damage to oral soft tissues, prone to dental caries and other oral diseases, and may cause a series of problems such as speech barriers and anorexia, causing great harm to patients. Inconvenient, greatly reducing the patient's quality of life

[0004] In response to the above problems, some artificial saliva products are currently on the market abroad, and there are some research reports in China, but there is no molded product on the market for patients to use.

The Chinese patent application number is 95111253.8, which discloses a kind of artificial saliva and its preparation method which is prepared by mixing various inorganic salts, preservatives and sterile distilled water. Poor, easily lost and other problems, the above-mentioned technology has not been applied, and there is no domestic drug that can effectively relieve various symptoms caused by xerostomia.

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