Iron (III)-carbohydrate based phosphate adsorbent

A phosphate adsorbent, carbohydrate technology, applied in the direction of iron compounds, iron organic compounds, iron group organic compounds without C-metal bonds, etc., can solve the problems of low adsorption capacity of phosphate adsorbents and low patient compliance.
CN101563295AActive Publication Date: 2009-10-21ELANCO
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ELANCO
Publication Date
2009-10-21

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Abstract

The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphatemia.
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Description

[0001] The present invention relates to novel iron-containing phosphate adsorbents, processes for their preparation, their use and pharmaceutical compositions containing them. Background of the invention

[0002] Phosphorus is critical for bone mineralization, cellular structure, genetic code and energy metabolism. It exists in many organic and inorganic forms. Phosphorus is present in almost all foods, and gastrointestinal absorption in dietary form is very efficient. Phosphorus homeostasis is usually maintained by several mechanisms (renal excretion, cellular release, hormone regulation, etc.). Hyperphosphatemia occurs when phosphorus loading (from gastrointestinal absorption, exogenous administration, or cellular release) exceeds renal excretion and tissue absorption.

[0003] Hyperphosphatemia is associated with significant increases in mortality and morbidity and can induce serious complications such as hypocalcemia, decreased vitamin D production, and migratory calcifi...

Claims

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