Method for producing water soluble moistureproof film coating premixing agent

Abstract

The invention discloses a method for producing a water soluble moistureproof film coating premixing agent, which relates to a pharmaceutical excipient. The premixing agent consists of raw materials, namely polyvinyl alcohol, polyethyleneglycol, hydroxypropyl methylcellulose, castor oil, tween-80, color lake, titanium pigment and talcum. The raw materials are mixed according to certain weight percentage, and the premixing agent is produced according to the prior process for producing the film coating premixing agents. The method has the advantages that the water soluble moistureproof film coating premixing agent produced according to the formula has good film-forming property, firm combination of a coating layer and a medicament core, strict wrapping, uniform thickness and even coloration, is smooth and beautiful, has good moisture resistance and oxygen insulation, can avoid surface abrasion, edge cracking, peeling or adhesion of a finished coating agent product and the like, and can better meet various needs of film coatings of solid pharmaceutical preparations.

Description

One: technical fields: [0001] The invention relates to a pharmaceutical auxiliary material, in particular to a water-soluble moisture-proof film coating premix for traditional Chinese medicine tablets. Two: background technology: [0002] Film coating is to uniformly spray a layer of relatively stable polymer material on the surface of solid pharmaceutical preparations by spraying to form a plastic film layer with a thickness of several microns. Now film coating has not only been widely used in Chinese and Western medicine tablets and pills, but also in small tablets, small pills, granules, soft and hard capsules and drug powders; it is suitable for all kinds of people. Film coating agents have many obvious advantages; the manufacturing process of sugar-coated tablets is complicated, and it will greatly increase the weight of the tablet core, which is difficult to take and absorb, rough in appearance and uncomfortable in taste; at the same time, the coating time of sugar-coa...

AI Technical Summary

Problems solved by technology

Film coating agents have many obvious advantages; the manufacturing process of sugar-coated tablets is complicated, and it will greatly increase the weight of the tablet core, which is difficult to take and absorb, rough in appearance and uncomfortable in taste; at the same time, the coating time of sugar-coated tablets is Long, usually takes 16 hours, long production cycle, high production cost, and because sugar-coated tablets contain a lot of talcum powder and sugar, there are certain restrictions on the number of people taking it

Although the film coating agents on the market now have certain moisture-proof and oxygen-barrier effects, they are not satisfactory. The moisture-proof and oxygen-barrier effects of general film coating agents are very weak and cannot meet the requirements of customers.