68results about How to "System stability" patented technology

The invention discloses a construction method of an agrobacterium tumefaciens mediated masson pine genetic transformation system, and belongs to the technical field of genetic engineering. According to the construction method of the agrobacterium tumefaciens-mediated masson pine genetic transformation system, immature masson pine cones are collected, embryogenic calluses are induced and cultured, the embryogenic calluses of the masson pine in a PEM III stage are used as a material, suspension pre-culture is performed to obtain an acceptor material, and the acceptor material is subjected to genetic transformation to obtain the agrobacterium tumefaciens-mediated masson pine genetic transformation system. The method comprises the following steps: firstly, carrying out tissue culture on a transgenic somatic embryo, infecting by adopting an agrobacterium infection solution with an OD600 value of 0.2-0.6, carrying out co-culture, recovery culture and screening culture, carrying out histochemical staining by adopting GUS, carrying out molecular identification to obtain a transgenic embryogenic callus, and carrying out maturation treatment to finally obtain the transgenic somatic embryo. The masson pine genetic transformation system established by the invention is stable in transformation performance and high in transformation positive rate, and when an acceptor material is masson pine embryonic callus with the genotype of 1-3-5, the transformation positive rate is as high as 100%.

The invention discloses pre-swelling multipolymer high-viscoelastic asphalt modified particles and a preparation method thereof, and belongs to the technical field of road engineering materials. The pre-swelling multipolymer high-viscoelastic asphalt modified particles are prepared from the following components in parts by weight: 10 to 40 parts of desulfurized waste tire rubber powder, 20 to 30 parts of styrene-butadiene-styrene block copolymer, 15 to 20 parts of adhesive, 10 to 17 parts of compatilizer, 13 to 18 parts of tackifier and 2 to 5 parts of auxiliary agent. In the pre-swelling multi-polymer high-viscoelastic asphalt modified particle provided by the invention, the desulfurized waste tire rubber powder is pre-swelled in the compatilizer, and the SBS develops in advance in the asphalt adhesive to form a continuous phase system which is not easy to deform and has a certain degree of elastic property with asphalt; according to the preparation method, high-volume desulfurized waste tire rubber powder and SBS in the prepared modified particles can be stably dispersed in matrix asphalt, the performance is rapidly improved, the construction workability is improved, and the modified particles have the advantages of good viscoelasticity, adjustment and optimization as required, stable system, high economic benefit and the like.

The invention discloses a hybrid energy storage system applied to independent photovoltaic power generation. The hybrid energy storage system comprises a photovoltaic array, a load, a lithium battery and a super capacitor. The photovoltaic array is connected with the DC bus through the boost converter. The lithium battery is connected with the direct current bus through a DC / DC bidirectional converter; the super capacitor is connected with the direct current bus through the other DC / DC bidirectional converter; due to the influence of the temperature on the lithium battery, the application of the hybrid energy storage system with the lithium battery is limited, the normal operation of the lithium battery can be influenced by over-high temperature, and the stability and the safety performance of the whole independent photovoltaic power generation system can also be influenced. Through a power distribution method, when an external environment of a photovoltaic system changes and a load fluctuates, threshold limitation is carried out on charging and discharging power of a lithium battery so as to ensure long-time safe operation of the lithium battery to compensate power imbalance caused by fluctuation, and thus stability of a bus voltage is maintained; energy distribution can be effectively adjusted according to system energy changes, and system stability and safety are maintained.

The invention discloses a fluralan nanostructure lipid carrier and a preparation method thereof, and belongs to the technical field of insecticide preparation, fluralan nanostructure lipid carrier semisolid cream can be orally taken or externally applied and is used for preventing and treating ectoparasitic diseases of pets such as dogs and cats; quantitative polyol is added into the water phase to be compounded with the lipid, so that the performance of the nano-structure lipid carrier is improved, the nano-structure lipid carrier system is more stable and high in encapsulation efficiency, release and absorption of a main drug in the nano-structure lipid carrier are improved, the problem of solubility of the fluralana is solved, bioavailability is improved, and the preparation method is suitable for industrial production. The traditional Chinese medicine composition promotes the medicine to play a better curative effect in vivo, so that the treatment effect is improved while the dosage of pets is reduced, the safety of the medicine is improved, the damage to the pets is reduced, and the traditional Chinese medicine composition has remarkable clinical application value.

According to the quick-drying water-based acrylic resin emulsion for the plastic printing ink and the preparation method thereof, when the core-shell emulsion is designed, the drying speed of the water-based acrylic resin emulsion for the plastic printing ink is regulated and controlled by changing the content of the hard monomer in the core-shell component; meanwhile, a cross-linking monomer capable of improving the drying speed of the emulsion is also added, so that the drying speed of the plastic ink is controllable by designing the water-based acrylic resin emulsion with different core-shell ratios, the process is relatively simple, the emulsion stability is good, and the cost is low. The prepared water-based acrylic resin emulsion for the quick-drying plastic ink has relatively good adhesive force and printing performance.

The invention belongs to the technical field of sealants, and discloses a low-modulus high-elongation antifouling weather-resistant sealant, a preparation method and application thereof, the low-modulus high-elongation antifouling weather-resistant sealant comprises the following raw materials by weight: 100 parts of alpha, omega-dihydroxy polysiloxane, 80-200 parts of an inorganic filler, 10-30 parts of a cross-linking agent, 1-4 parts of a coupling agent, and 2-10 parts of a titanate vulcanizing agent; wherein the inorganic filler comprises active calcium carbonate and modified talcum powder; the modified talcum powder is prepared by sequentially carrying out layered stripping and modification treatment on talcum powder. The low-modulus and high-elongation antifouling sealant provided by the invention can be well suitable for joint sealing during repair of ancient buildings, and meanwhile, the product can also be extended to the field of sealing of other low-modulus antifouling buildings with the same requirements, and has high economic value.

The invention relates to the technical field of road materials, in particular to environment-friendly rubber modified asphalt as well as a preparation method and application thereof. The environment-friendly rubber modified asphalt is prepared from the following components in parts by mass: 100 parts of matrix asphalt; 1-5 parts of softening oil; the softening oil comprises aromatic oil, oleic acid, furfural extract oil and wax oil; 15 to 30 parts of micro-nano rubber particles; the micro-nano rubber particles are obtained from desulfurized and activated reclaimed rubber; 0.1 to 0.3 part of a stabilizing agent; and 0-3 parts of a high-molecular polymer. Compared with common rubber modified asphalt, the environment-friendly rubber modified asphalt disclosed by the invention has higher viscosity, excellent low-temperature performance and high-temperature performance, a stable system and environment-friendly construction environment, and the odor in the construction process is greatly reduced. The environment-friendly rubber asphalt is prepared by adopting an environment-friendly rubber particle wet method, the preparation process is simple, high-standard modified asphalt can be obtained through one-time feeding and a colloid mill, and the production cost is saved.

The invention discloses a chromium-free pretreatment solution, a chromium-free color-coated sheet and a preparation method of the chromium-free color-coated sheet, and belongs to the technical field of metal material surface treatment and protective coatings. The pretreatment liquid comprises a water-soluble carboxyl-containing organic matter, phosphate, a strong oxidant and inorganic acid, and is prepared through step-by-step mixing, and a compact pretreatment layer is formed on the surface of the hot-dip galvanized sheet by utilizing the synergistic complexing effect among the components. The pretreatment liquid is applied to a base plate in a roller coating mode, after curing is conducted at the temperature of 70-150 DEG C, chromium-free primer, finish paint and back paint are sequentially applied, and the chromium-free color-coated plate is obtained after baking. The obtained color-coated sheet has excellent corrosion resistance and adhesive force, the color-coated sheet is chromate-free in the whole process, and the dual requirements for environmental protection and performance in the fields of household appliances and the like are met.

The invention provides a composition, an ionic gel coating and a preparation method and application thereof, the composition contains fluorine-containing polyamide acid, ionic liquid, a surfactant and an additive, and the mass ratio of the fluorine-containing polyamide acid to the ionic liquid to the surfactant to the additive is (20-60): (1.5-27): 1: (40-60). According to the composition disclosed by the invention, the ionic liquid with low condensation point, non-volatility and chemical stability is locked in the fluorine-containing polyimide with high and low temperature resistance and excellent mechanical properties, and the surface active agent and the additive are coupled with the fluorine-containing polyimide, so that the whole material has relatively high hydrophobicity and transparency; and meanwhile, the coating has multiple functions of room-temperature self-repairing, self-cleaning and the like, has relatively high binding force with the surface of a base material such as stainless steel and the like, and can reduce the ice adhesion strength of the surface to a great extent and improve the robustness of the low ice adhesion performance of the material in an extremely low-temperature environment.

The invention provides a refining method of methyl diene diketone. By utilizing the method, unknown single impurities in methyl diene diketone sold in the market at present can be removed, and high-purity methyl diene diketone is obtained.

The application discloses black soldier fly oil freeze-dried liposomes and a preparation method thereof. The preparation method of the black soldier fly oil freeze-dried liposomes comprises the following steps: dissolving phospholipid, sterol, black soldier fly oil and a surfactant in an organic solvent to form a film, hydrating the film with a buffer solution, and preparing nano-liposomes through pulse ice bath ultrasonic treatment; adding a freeze-drying protective agent, uniformly mixing, pre-freezing, and freeze-drying, so as to obtain the black soldier fly oil freeze-dried liposomes. The stability of the black soldier fly oil is remarkably improved through the freeze-drying process, long-term storage of the liposomes at room temperature is realized, and a new strategy is provided for the development of a functional oil delivery system.

The invention belongs to the technical field of synthesis of organic compounds, and relates to a synthesis method of drometrisiloxane, which comprises the following steps: carrying out Williamson etherification reaction on an ultraviolet light absorber UV-P and methyl allyl chloride to obtain an intermediate I; carrying out Claisen rearrangement reaction on the intermediate I to obtain an intermediate II; and carrying out hydrosilylation reaction on the intermediate II and heptamethyltrisiloxane to obtain dromethicone, the Williamson etherification reaction comprises the following steps: dissolving an ultraviolet light absorber UV-P in an alcohol ether solvent, and reacting with methyl allyl chloride under the condition of an acid-binding agent. According to the synthesis method of the drometrisiloxane, the etherification reaction is efficient, simple and convenient, the hydrosilylation reaction catalyst is high in efficiency, the solvent system is green and economical, the overall process is high in yield and purity, and the product quality is excellent.

This invention belongs to the field of pharmaceutical preparations, specifically relating to a method for preparing and applying a multivitamin for injection. The multivitamin for injection of this invention includes water-soluble vitamins, fat-soluble vitamins, glycocholic acid, phospholipids, and water. The preparation process of this invention does not involve the addition of organic solvents or surfactants. Technically, it achieves a safe and simple mixed micelle preparation process using only water as a solvent, reducing adverse reactions in clinical use and ensuring clinical safety. It has been industrialized and scaled up for production, and is a highly safe and stable multivitamin injection formulation that can be industrially produced.

The application is suitable for the technical field of inorganic substance preparation method, and provides a preparation method of bromine, which comprises the following steps: step one: a certain amount of sodium bromide and hydrobromic acid are added into a mother liquor pool and stirred to obtain a mother liquor; step two: a predetermined amount of stearic acid and polyvinylpyrrolidone are added; step three: preheating is carried out, and then the preheating is fed into an absorption tower; step four: the liquid at the bottom of the absorption tower flows into the upper part of a bromine evaporation tower, and is heated by steam in the bromine evaporation tower; water vapor and chlorine gas are introduced from the bottom of the bromine evaporation tower, and bromine steam enters the absorption tower; step five: the distillation acid liquid generated by the bromine evaporation tower flows into a preheater to be preheated; bromine steam flows out from the upper part of the bromine evaporation tower to obtain a bromine and water mixture; step six: the bromine and water mixture flows into a bromine water separation bottle to be separated, and bromine products are obtained, thereby, the bromine source is hydrogen bromide and sodium bromide; the stearic acid can effectively reduce the surface tension, so that the reaction is more uniform, and the system is stable.

The invention discloses a power failure protection system for a small AI cloud server, and relates to the technical field of direct-current power supply electronic equipment. A direct-current power supply input module in the system is connected with an external direct-current power supply; the system power supply module supplies power to the AI cloud server; the charging power supply generation module converts an input voltage into a stable voltage for charging; the farad capacitor charging and discharging module stores electric energy; when the full charge monitoring module monitors that the farad capacitor charging and discharging module is fully charged, a full charge signal is output; the power-down monitoring module outputs a power-down signal when monitoring that the external direct-current power supply is powered down; the CPU responds to the full electric signal and controls the charging power supply generation module to stop outputting; and responding to the power failure signal, executing a data protection process, controlling the standby power switch module to be switched on, and switching to the farad capacitor charging and discharging module to supply power to the AI cloud server, so that rapid seamless power switching and reliable data protection of the small AI cloud server during power failure are realized, the cost is low, and the reliability is high.

The invention relates to a soap-based facial cleanser and a preparation method thereof. The soap-based facial cleanser comprises the following components: fatty acid potassium salt, an ampholytic surfactant, an amino acid surfactant, a polymer and water, the polymer comprises corn starch, an acrylic acid (ester) copolymer and polyquaternium-6. According to the soap-based facial cleanser disclosed by the invention, the fatty acid potassium salt, the ampholytic surfactant and the amino acid surfactant are matched for use, so that a system is stable and is not easy to change color and smell, the facial cleanser has the advantages of a soap-based system, is rich in foam and good in cleaning power, does not cause excessive cleaning, and the used components are mild and non-irritant, so that the soap-based facial cleanser is convenient to use. The skin of a consumer is more moist after use, and the comfort is better.

This invention discloses a cockroach attractant and its application. The attractant is characterized by the following raw materials: 5-hydroxyfurfural. The cockroach attractant of this invention solves the problem of poor effectiveness of existing cockroach attractants. It utilizes the synergy of the components to form an enhanced cockroach attraction system, which greatly improves the attraction effect of cockroaches.

This invention discloses a lutein composition for relieving eye fatigue and its preparation method, belonging to the field of functional foods. The process involves: reacting phycocyanin and kelp polyphenols to obtain modified phycocyanin; reacting fucoidan and β-glucuronidase to obtain modified fucose; reacting fish collagen peptides and zinc chloride to obtain collagen peptide-zinc chelate; reacting lutein silica cage complex and modified phycocyanin to obtain a first complex; reacting the first complex and modified fucose to obtain a second complex; reacting the second complex, collagen peptide-zinc chelate, and krill oil to obtain a lutein complex; reacting the second complex, collagen peptide-zinc chelate, and krill oil, then adding trehalose to obtain the lutein complex; and finally mixing the lutein complex with maltodextrin to obtain the lutein composition.

The embodiment of the invention provides a method and device for improving the recovery efficiency based on CO2 microbubbles and forward pressure driving. The method comprises the steps that on-site injection parameters are obtained, the on-site injection parameters comprise the pressure flooding agent injection amount, the pressure flooding agent injection speed, the soaking time and the CO2 microbubble gas-liquid ratio, and the on-site injection parameters are injection parameters corresponding to the target recovery ratio in multiple recovery ratios; the multiple recovery rates are obtained by conducting petroleum simulation recovery on the target well based on different injection parameters; the target recovery rate is the highest recovery rate in the maximum change rate; according to the pressure flooding agent injection amount and the pressure flooding agent injection speed, a pressure flooding agent is injected into the target well; according to the soaking time, soaking treatment is conducted on the target well injected with the pressure flooding agent; cO2 microbubbles are injected into the target well subjected to soaking treatment, and the CO2 microbubbles are obtained according to the gas-liquid ratio of the CO2 microbubbles; and oil recovery is conducted on the target well injected with the CO2 microbubbles. According to the method, the recovery efficiency can be improved.

The application discloses a deep-groove polysilicon etching solution, which comprises an oxidizing agent, an inorganic acid, a pH regulator and a surfactant. The deep-groove polysilicon etching solution can efficiently etch polysilicon while ensuring the uniformity and smoothness of the etching surface, and can maximize the consistency of the etching of the upper and lower grooves and the smoothness of the surface. In the etching process, the inorganic acid ensures that the etching solution system is in an acidic environment, and the polysilicon is etched; the pH regulator avoids the large fluctuation of the pH of the etching solution, thereby ensuring the stability of the polysilicon etching process; and the surfactant reduces the surface tension of the etching solution, improves the wettability of the etching solution, ensures the consistency of the etching rate of the upper and lower grooves, and ensures the consistency of the groove aperture.

The invention belongs to the technical field of high polymer materials, and relates to a low-pressure-change, low-precipitation and high-weather-resistance bio-based extrusion grade TPV composite material as well as a preparation method and application thereof. According to the invention, the bio-based EPDM is used as a matrix material, the usage amount of a petroleum-based material is reduced, so that carbon emission is reduced, the realization of a carbon neutralization target is facilitated, and the environment-friendly material not only conforms to the concept of sustainable development, but also can reduce the influence on the environment on the premise of not influencing the performance. A cross-linked network structure formed by a phenolic aldehyde vulcanization system is more compact and uniform, the possibility of precipitation is reduced, phenolic aldehyde resin and a rubber phase have good compatibility, the whole system is more stable, and the prepared bio-based extrusion grade TPV material generates less die material slag accumulation in the extrusion process, so that the extrusion quality of the TPV material is improved. Therefore, the production efficiency and the appearance quality of the material are improved.

The application discloses a concentrated liquid for hydraulic support based on coal-based Fischer-Tropsch synthesis technology and a preparation method thereof, and particularly relates to the technical field of hydraulic support concentrated liquid, and comprises the following components: coal-based Fischer-Tropsch synthesis oil derivative lubricant 30-45%, gasification cinder modification additive 5-12%, composite antirust agent 8-15%, non-ionic emulsifier 10-18%, freeze-thaw stabilizer 3-8%, and water in excess. The concentrated liquid takes the Fischer-Tropsch synthesis oil derivative as a core lubricating component, and is combined with the gasification cinder modification additive and the like, so that the problem of soap precipitation caused by high-hardness mine water is effectively solved, the concentrated liquid has good freeze-thaw resistance and environmental protection, meets the current environmental protection standard, and is particularly suitable for the high-mineralization mine area environment in Shanxi.

The invention relates to the field of food, in particular to drinking type normal-temperature yoghurt and a preparation method thereof.The preparation method of the drinking type normal-temperature yoghurt comprises the steps that a fermented yoghurt base material and a glue solution are mixed, and dynamic smoothing, homogenizing, sterilizing, cooling and filling are sequentially conducted; wherein the difference between the pH value of the glue solution and the pH value of the yoghurt base material is not more than 0.2; a dynamic smoothing pump is adopted for dynamic smoothing, and the frequency of the dynamic smoothing pump is 30-60 Hz; the homogenizing pressure is 20 to 60 bar. The difference between the pH value of the glue solution and the pH value of the yoghurt base material is controlled not to exceed 0.2, and the glue solution and the yoghurt are completely mixed under the combined action of dynamic smoothing and low-pressure homogenization, so that the smooth mouth feel and the system stability of the yoghurt are realized, and the mode of increasing the dosage of a stabilizer which is not favored by consumers is not adopted.

The present application discloses a flurana nanostructured lipid carrier and a preparation method thereof, which belongs to the technical field of insecticide preparation. The flurana nanostructured lipid carrier semisolid cream can be administered orally or externally, and is used for preventing and treating ectoparasitic diseases of pets such as dogs and cats. The present application improves the performance of the nanostructured lipid carrier by adding a quantitative polyol to the aqueous phase and compounding with lipids, which not only makes the nanostructured lipid carrier system more stable and has a high encapsulation rate, but also improves the release and absorption of the main drug in the nanostructured lipid carrier, solves the solubility of flurana, and improves the bioavailability, promotes the drug to better exert its therapeutic effect in the body, enables pets to improve the therapeutic effect while reducing the dosage of the drug, improves the safety of the drug, reduces the damage to the pet, and has significant clinical application value.

The invention relates to the field of coal liquefaction, in particular to a preparation method and system of coal-based heat-conducting oil, coal-oil slurry is prepared by mixing pulverized coal and a hydrogen-donating solvent, and the coal-based heat-conducting oil is finally prepared by the steps of direct coal liquefaction, hydrotreating, two-time oil-gas separation, light and heavy component separation, steam stripping rectification, reduced pressure distillation and the like in sequence. The invention also provides a corresponding preparation system which integrates core equipment such as a mixing tank, a coal liquefaction reactor, a hydrogenation reactor, a fractionating tower, an oil-gas separator, a light-heavy separator, a stripping tower and a vacuum tower. A new process route for preparing the heat conduction oil is developed, a traditional preparation method for generating the heat conduction oil by extracting aromatic hydrocarbon from petroleum-based light oil through catalytic cracking is broken through, and the obtained heat conduction oil has high initial boiling point and flash point and stable heat conduction capability at high temperature.

The application provides a high-efficiency expansion culture method of umbilical cord blood gamma delta T cells and application thereof, and belongs to the technical field of biological medicine. Through a specific two-stage strategy of "initial induction culture + expansion culture", the application is simple in operation, stable in system, and high in success rate, effectively overcomes the defects of limited autologous blood source, unstable expansion and low cell activity in the prior art, and lays a foundation for large-scale preparation and allogeneic application of gamma delta T cells. The umbilical cord blood gamma delta T cells obtained by the method of the application are excellent in quantity, purity, activity and anti-tumor function, and have stronger tumor cell killing ability, and are especially suitable for adoptive immunotherapy. The application breaks through the technical bottleneck of the traditional culture system, provides a high-efficiency, stable and clinically convertible gamma delta T cell expansion scheme, and has important application prospect and market value.

This application relates to the field of daily chemical technology, specifically disclosing a herbal compound nasal congestion-relieving essential oil composition and its processing method. The composition is prepared from a compound nasal congestion-relieving base oil obtained by mixed extraction of Magnolia biondii, Xanthium sibiricum, and Angelica dahurica, menthol rosmarinic acid ester, a homologous regulator of esterase activity, natural borneol extracted from natural plants, and medium-chain triglycerides. The homologous regulator of esterase activity is selected from oleanolic acid or crataegolic acid. The preparation method is as follows: first, the compound nasal congestion-relieving base oil is prepared by supercritical extraction; then, menthol rosmarinic acid ester is obtained through enzymatic synthesis; subsequently, the base oil undergoes micro-trace enzyme anchoring modification; finally, the components are mixed through a gradient phase fusion process and bottled to obtain the finished product. This composition can be used to relieve nasal congestion symptoms caused by acute rhinitis and allergic rhinitis, and has the advantages of stable nasal congestion-relieving effect, long duration of action, and low mucosal irritation. The preparation method is green and environmentally friendly, the product has high purity, and good batch-to-batch consistency.

The invention relates to a method for preparing a high-toughness and high-conductivity PIPD-enhanced graphene fiber. The method comprises the following steps: mixing a graphene oxide solution and a PIPD solution to prepare a spinning solution, adopting two coagulation baths to perform wet spinning, and sequentially performing chemical reduction and vacuum drying after spinning to obtain the high-toughness and high-conductivity PIPD-enhanced graphene fiber. The PIPD content in the spinning solution is 0.1-50wt% of the graphene oxide. The first coagulation bath is a metal ion / phosphoric acid aqueous solution, and the second coagulation bath is an ethanol / water mixed solution. The high-toughness and high-conductivity PIPD-enhanced graphene fiber has an elongation at break of 2-20%, an ultimate tensile strength of 250-1500 MPa, and a fracture toughness of 10-70 MJ / m 3 , the conductivity is 10 2 ~10 6 S·m ‑1 The present invention toughens the graphene fiber by adding a small amount of PIPD, thereby improving the mechanical properties of the graphene fiber and having good electrical conductivity.

The invention provides a non-viral vector for treating phenylketonuria as well as a preparation method and application of the non-viral vector, and belongs to the technical field of biological pharmacy. The non-viral vector for treating phenylketonuria comprises a lipid vector and a nucleic acid molecule for editing PAH gene expression, the lipid carrier comprises a cationic lipid and an auxiliary lipid, and the auxiliary lipid comprises a pH sensitive lipid component and an immune escape promoting lipid component; the nucleic acid molecule for editing PAH gene expression comprises DNA (deoxyribonucleic acid), siRNA (small interfering ribonucleic acid), mRNA (messenger ribonucleic acid) or sgRNA. The non-viral vector is prepared by screening lipid components and proportions. The non-viral vector prepared by the invention is uniform in particle size and stable in system, can wrap or load a gene editing drug, is high in drug encapsulation efficiency, has relatively high drug delivery efficiency for hepatocytes, can obviously recover the phenylalanine hydroxylase level, and achieves the effect of treating phenylketonuria.

The present invention discloses a soluble azelaic acid supramolecular combination system with soothing effect, belonging to the field of supramolecular technology. The preparation method of the soluble azelaic acid supramolecular combination system with soothing effect in the present invention comprises the following steps: mixing azelaic acid, ectoine and panthenol in a molar ratio of 1:0.2-3:1-10, heating at 70-110°C for 2-16h in an atmosphere of nitrogen, argon or air, so that azelaic acid, ectoine and panthenol form supramolecular through hydrogen bonds, and thus a soluble azelaic acid supramolecular combination system with soothing effect is obtained. The maximum content of azelaic acid in the soluble azelaic acid supramolecular combination system prepared by the present invention can reach 45%, and the soluble azelaic acid supramolecular combination system has high solubility and stability in water, and a large amount of water is added to the system to keep the system stable, so that the mass concentration of azelaic acid in the aqueous solution can be 0.3%-35% without precipitation.