The invention discloses a lincRNA
small peptide coding potential identification method and a lincRNA
small peptide coding potential
identification system, and belongs to the technical field of
computer technology and
bioinformatics. The method comprises the following steps: firstly,
processing a lincRNA sequence into a standardized sequence set; identifying and integrating the deduplicated potential coding fragments to obtain a candidate
coding region set; after extracting multi-dimensional feature codes of each region, performing fusion through a Mama model and a
machine learning model to obtain a fusion prediction confidence coefficient and a
label; and finally, judging the coding potential, if not, outputting a conclusion, if yes, deducing an
amino acid sequence, calculating comprehensive sequencing confidence by combining multiple indexes, sequencing, and screening
small peptide sets with high and
low confidence according to a threshold value. According to the method, an efficient sequence
state space modeling structure is introduced, dependence on
ribosome sequencing or
mass spectrum data is not needed, high-precision, low-complexity and extensible prediction of the potential small
peptide coding capacity in the lincRNA sequence is achieved, and the technical defect that accuracy and calculation efficiency are difficult to consider at the same time in an existing method is overcome.