Method preparing apigenin and application thereof

A technology of apigenin and celery, applied in the field of health care products, can solve the problems of unsatisfactory treatment and health care effects, excessive consumption of raw materials, low purity of apigenin, etc., and achieves the effects of improving immunity, reducing processing costs, and easily obtaining raw materials

Inactive Publication Date: 2009-12-30
JILIN PROVINCE WEIYI BIOENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the procedures involved in the existing apigenin preparation methods are relatively complicated, and the purity of the obtained apigenin is relatively low, thus causing excessive consumption and waste of r

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The powdered apigenin and the oily deep-sea fish oil are put into a stirring device for preparation, so that the apigenin and the deep-sea fish oil can be fully fused to obtain a mixture, which is then loaded into capsules. The weight of raw materials in each capsule is 500mg, wherein, the apigenin is 150mg, and the deep-sea fish oil is 350mg.

Embodiment 2

[0029] The powdered apigenin and the oily deep-sea fish oil are put into a stirring device for preparation, so that the apigenin and the deep-sea fish oil can be fully fused to obtain a mixture, which is then loaded into capsules. The weight of raw materials in each capsule is 500mg, wherein, apigenin is 180mg, and deep-sea fish oil is 320mg.

Embodiment 3

[0031] The powdered apigenin and the oily deep-sea fish oil are put into a stirring device for preparation, so that the apigenin and the deep-sea fish oil can be fully fused to obtain a mixture, which is then loaded into capsules. The weight of raw materials in each capsule is 500mg, wherein, the apigenin is 200mg, and the deep-sea fish oil is 300mg.

[0032] Case 1:

[0033] The main component of apigenin is: acegenin. The pharmacological effects of apigenin are: promoting blood circulation, removing blood stasis, resisting myocardial ischemia, reducing myocardial oxygen consumption, and improving myocardial function. For the treatment of ischemic heart disease, relieve angina and myocardial ischemia, lower cholesterol and triglycerides.

[0034] Treat 35 patients with hyperviscosity, once a day, orally, one capsule each time, after six weeks of treatment. It was found that data such as cholesterol, triacylglycerol, blood viscosity, platelet aggregation and thrombus index a...

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PUM

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Abstract

The invention relates to a method for preparing apigenin, which comprises the following steps: after screening and pulverizing celery seeds, placing the celery seeds into an alcohol container with the content of 70 percent, stirring the celery seeds and then leading the celery seeds to stand; after fusing the powdery celery seeds and alcohol, changing the powdery celery seeds into a granular mixture; extracting the granular mixture in the container for three times, the time interval of extraction each time is two hours; filtering the extracted granules by a solution and decompressing and concentrating the extracted granules so as to prepare the powdery refined apigenin, wherein the purity of the extracted refined apigenin is 98 percent. The method is used for preparing the powdery apigenin and oily deep sea fish oil and placing the powdery apigenin and the oily deep sea fish oil into a capsule, and each capsule has the weight of 500 mg after raw material are proportioned and comprises 150 mg-200 mg of apigenin and 300 mg-350 mg of deep sea fish oil. The invention has the effects of regulating the blood pressure and the blood fat, resisting the oxidation, improving the immunity, delaying the aging, and the like.

Description

technical field [0001] The invention relates to the field of health products, in particular to a preparation method and application of apigenin. Background technique [0002] Apigenin (apigenin) belongs to flavonoids, and is abundant in the leaves of Apiumgraveolens var. dulce; the whole herb of Selaginella tamariscina; and the leaves of Sabinachinenesis. Apigenin exists in a variety of plants in the form of plant yellow pigment. The pure product is a yellow powder, odorless and tasteless, and is a natural antioxidant. According to literature reports, apigenin is said to have the effects of lowering blood pressure, affecting the central nervous system, anti-virus, inhibiting enzyme activity, and resisting free radicals. [0003] However, the processes involved in the existing apigenin preparation methods are relatively complicated, and the purity of the obtained apigenin is low, thus causing excessive consumption and waste of raw materials. In addition, in the application ...

Claims

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Application Information

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IPC IPC(8): C07D311/30A61K9/66A61K31/352A61K36/23A61P39/06
Inventor 崔淑艳
Owner JILIN PROVINCE WEIYI BIOENG
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