Metal ion imprinting solid phase extraction small column, preparation and application thereof

Abstract

The invention relates to a metal ion imprinting solid phase extraction small column, which comprises the small column which takes a metal ion imprinting absorbent of 50-200mg as a filling matrix and has a polypropylene outer shell with the diameter of 6-10mm; and the preparation comprises the steps of dissolving metal ions, CTMAB and functional monomers in DDW, adding a mixed sol of alkoxy silane and methanol, further adding a catalyst, stirring, filtering and drying; then placing in a Soxhlet extractor, removing the CTMAB and the metal irons, washing and drying for preparation; and weighing the metal ion imprinting absorbent, filling in the solid phase extraction small column with the polypropylene outer shell and filling the column by homogenization under the vacuum-pumping state. The filler synthesis process of the solid-phase extraction small column is simple, the cost is low, the reaction conditions are mild, the prepared metal ion imprinting solid phase extraction small column can be applied in selective separation and enrichment of trace metal ions in environmental water samples, compared with the ordinary liquid-liquid extraction method, the operation is simple, rapid and highly efficient.

Description

technical field [0001] The invention belongs to the field of molecularly imprinted solid phase extraction column and its preparation and application, in particular to a metal ion imprinted solid phase extraction column and its preparation and application. Background technique [0002] Due to the low content of heavy metal elements in environmental and food samples, and the complex components and many interferences of environmental and food samples, they usually have to be separated and enriched before analysis and determination. The purpose of separation and enrichment is to concentrate trace metal ions, reduce the minimum detection concentration, remove interfering substances, and improve the accuracy and sensitivity of the determination. Liquid-liquid extraction is a widely used technology for pre-enrichment and separation of metal ions. Although this technology has a high enrichment rate and good reproducibility, the operation process is cumbersome, time-consuming, and us...

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Problems solved by technology

[0004] After searching the prior art, it is found that the synthesis of molecularly imprinted-sol-gel materials generally adopts the surface imprinting method (Dai, et al. Imprint-coating synthesis of selective functionalized ordered mesoporous sorbents for separation and sensors. USP, 6,251,280, June 26, 2001; Fang Guozhen, Tan Jin, Yan Xiuping. Synthesis method and adsorption material of sulfhydryl functionalized adsorption material imprinted with cadmium ions on the surface of silicon balls, CN, 1621146, 2005, 6). The disadvantage is that the adsorption capacity of the adsorbent is limited , the adsorption selectivity also needs to be improved