Preparing method of mannich base
Patent Information
- Authority / Receiving Office
- CN Β· China
- Current Assignee / Owner
- ANYANG NORMAL UNIV
- Publication Date
- 2010-06-02
- Estimated Expiration
- Not applicable Β· inactive patent
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Abstract
Description
1. Technical field:
[0001] The invention relates to a method for preparing a Mannich base, in particular to a three-component one-pot method for preparing a Mannich base by using aldehydes, amines, ketones or naphthols as raw materials, and belongs to the field of chemistry. 2. Background technology:
[0002] Mannich base (English: Mannich base) and its derivatives are an important class of nitrogen-containing compounds, widely used in medicines, pesticides, dyes, coatings, explosives, corrosion inhibitors, oil additives and other fields, or many organic Important intermediates in synthesis and natural product synthesis. The widespread existence and application of compounds containing nitrogen atoms reflect the importance of Mannich bases.
[0003] There are many ways to prepare Mannich base and its derivatives, and there are two main routes: one is to make imine from aldehyde and amine, and then react with ketone or silanol ether prepared from ketone to synthesize two comp...