Method for quickly detecting doping of benzodiazepine compound in food, medicine or health-care product

A medium benzodiazepine and detection method technology is applied in the field of rapid detection doped with benzodiazepines, and can solve the problem that the specific combination of a gold-labeled reagent and a test substance cannot be realized, and the colloidal gold immunity cannot be fully exerted. The advantages of chromatographic detection and the unknown amount of illegally adulterated benzodiazepines have achieved the effect of rapid screening, fast detection and low cost
CN101718787AInactive Publication Date: 2010-06-02广东省惠州市药品检验所

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
广东省惠州市药品检验所
Publication Date
2010-06-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for quickly detecting the doping of a benzodiazepine compound in a food, a medicine or a health-care product. The method comprises the following steps: firstly, preprocessing a sample to be measured, extracting the benzodiazepine compound which is added in an enriched transgression way and then combining with a colloidal gold immunological chromatographic method, thereby realizing the quick detection of the benzodiazepine compound added into the food, the medicine or the health-care product.The invention features wide coverage range of measured targets, simple operation, high detection speed and easy observation of a detection result, can realize the quick screening of a large number of samples, picks out the samples added with the benzodiazepine compound in a transgression way from a large number of samples, lowers the cost greatly and reduces the workload.The preprocessing method can effectively enrich the concentration of a substance to be measured, so the detection result is more sensitive and accurate.The invention is suitable for various common medicament forms in the food, the medicine or the health-care product, can fill up a system screening method which is absent in the industry, executes the supervision and control over the food and medicine market effectively and guarantees the safety of the diet and medicine of people.
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Description

technical field

[0001] The invention relates to the detection field of food, medicine or health products, in particular to a rapid detection method for doping of benzodiazepine compounds in food, medicine or health products. Background technique

[0002] With the increasingly fierce competition and increasing pressure in modern society, many people suffer from anxiety and depression, which induce sleep disorders and insomnia. Patients need to rely on drugs to relieve these symptoms. Commonly used drugs include diazepam (stable), alprazolam (jiajingan), estazolam, etc., which belong to the second class of psychotropic drugs, and their use is strictly restricted. For patients who need to take medicine for a long time, food with sedative and hypnotic effects, Chinese patent medicine or health food may become their first choice.

[0003] Benzodiazepines (BZ) are commonly used clinical sedative and hypnotic drugs at present. It overcomes many shortcomings caused by barbiturates....

Claims

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