Method for extracting and separating high-purity wild baicalin from breviscapinun

A technology of baicalin and breviscapine, which is applied in the field of extraction and separation of active components in plants, can solve problems such as resin residue, and achieve the effects of easy control, short time consumption and good reproducibility
CN101830951AInactive Publication Date: 2010-09-15CHENGDU PUSH BIOLOGICAL TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHENGDU PUSH BIOLOGICAL TECH
Publication Date
2010-09-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a high-efficiency separation method of high-purity wild baicalin, comprising the following steps of: (1) dissolving raw materials, wherein DMF (Dimethyl Formamide) is used as solvent dissolution-assistant raw materials; and (2) using methanol-DMF-water as a mobile phase, separating by adopting a high-efficiency preparation liquid-phase chromatographic column, recovering the solvents and drying to obtain a baicalin product with the purity greater than 99%. The method has the advantages of simplicity and rapidity, less solvent consumption, high yield, economy and environmental protection, can be used for preparing a great deal of products once and has higher economic value and academic value.
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Description

technical field

[0001] The invention discloses a method for quickly separating a large amount of high-purity scutellarin from scutellarin, and belongs to the technical field of extraction and separation of effective components in plants. Background technique

[0002] Erigeron breviscapus (Vant.) Hand.-Mazz., also known as Erigeron breviscapus (Vant.) Hand.-Mazz. Scutellarin, etc., wherein the content of scutellarin (Scutellarin) is about 80% (HPLC method detection) is its main active ingredient, also known as scutellarin, scutellarin, chemical name 3', 5, 6-tri Hydroxy-7-O-glucuronide, molecular formula C 21 h 18 o 12 , the structural formula is shown in formula I.

[0003] Formula I

[0004] Breviscapine has a significant clinical effect in the treatment of cardiovascular and cerebrovascular diseases, and has a large demand. It has been developed into various dosage forms such as injections, tablets, and capsules. Because scutellarin has poor water solubility and fa...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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