Application of Puer tea in preparing drugs for resisting immunosenescence or other relevant diseases

A technology of immune aging and Pu-erh tea, applied in the direction of drug combination, antidote, pharmaceutical formula, etc., to achieve the effect of enhancing immune function, inhibiting excessive inflammatory response, and expanding the scope of application

Inactive Publication Date: 2010-10-13
马治中 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It has not been reported so far to explore the efficacy of Puer tea and its extracts from the dual purposes of anti-immune aging and anti-inflammation

Method used

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  • Application of Puer tea in preparing drugs for resisting immunosenescence or other relevant diseases
  • Application of Puer tea in preparing drugs for resisting immunosenescence or other relevant diseases
  • Application of Puer tea in preparing drugs for resisting immunosenescence or other relevant diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The preparation of embodiment 1 Pu'er tea water extract

[0030] Take raw Pu-erh tea or cooked tea respectively, and crush them into coarse powder. Boiling water leaching three times, the mass ratio of tea leaves and water is 1:20; 1:20; 1:10 respectively; the leaching time is 20 minutes, 20 minutes, 10 minutes respectively. Combine the filtrates and concentrate under reduced pressure at 60°C to obtain a concentrated tea soup. Bottling and sterilizing the concentrated tea soup (120°C, 20 minutes), refrigerating at low temperature (4°C) for later use, or drying the extract in vacuum to obtain Pu'er tea extract.

Embodiment 2

[0031] The pharmacological activity research of embodiment 2 Pu'er tea extract

[0032] 1. Experimental drug:

[0033] Refer to Example 1 for the preparation process of Pu'er tea extract.

[0034] 2. Experimental animals:

[0035] The experimental animals were selected internationally recognized aging animal model - rapid aging substrain (Senescence accelerated mouse / prone, SAM-P8, male, 8 months old), and anti-rapid aging substrain (Senescence accelerated mouse / resistance, SAM-R1, male , 8 months old) were young control mice. Through oral gavage, the rapid aging mice were given different doses of raw Pu’er tea extract and cooked Pu’er tea extract, anti-rapid aging subline (youth control group) and rapid aging subline (old control group) respectively, of SAM-P8. The same amount of distilled water was given by intragastric administration every day for 4 weeks.

[0036] 3. Experimental method:

[0037] After 4 weeks of medication, the animals were anesthetized with ether, b...

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Abstract

The invention provides an application of Puer tea in preparing drugs for resisting immunosenescence or other relevant diseases. The invention makes research and analysis on the anti-immunosenescence fuction and the theory thereof of the Puer tea, proves that the Puer tea or an extractive thereof has dual functions of enhancing recessive immunity and restraining excessive inflammatory reaction of an aged organism under the action of reversing aged immunocyte ( reducing memorability T cells and increasing NK cells), realizes the purpose of preventing immunosenescence, expands the application range of the Puer tea or the extractive thereof, and provides a drug or health care product for effectivly preventing and / or treating the immunosenescence or the other relevant diseases.

Description

technical field [0001] The invention relates to a medicine for resisting immune aging or its related diseases, in particular to the use of Pu'er tea in the preparation of medicines or health care products for resisting immune aging or its related diseases. Background technique [0002] As a unique historical tea in Yunnan Province, Pu'er tea is well-known at home and abroad for its unique processing technology and health care function. However, most of the health functions of Pu'er tea are summed up from long-term experience or folklore, lacking scientific basis. At present, the research on the efficacy of Pu'er tea is mainly carried out on non-aging experimental animals. In the actual application process, Pu'er tea extract also has various health care effects on the elderly population, but the principle of the health care effect on the elderly population has not yet been definitively and scientifically elucidated. [0003] Immunosenescence refers to the phenomenon of prog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61P39/06
Inventor 马治中邵宛芳屠鹏飞张可马旭袁力丰张梁
Owner 马治中
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