Ganoderma Lucidum spore essential oil compound soft capsule preparation and preparation method thereof
A technology of soft capsule preparation and spore essential oil, which is applied in the fields of capsule delivery, anti-virus agents, and pharmaceutical formulas, etc., and can solve problems such as long-term delays, months or even years, heavy tasks, lack of anti-fatigue effects, etc. , to achieve high bioavailability, high extraction efficiency, and no excessive pesticide residues
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Embodiment 1
[0017] (1), raw material ratio: Ganoderma lucidum spore powder 1000g, ginseng 1000g, rhodiola rosea 1000g, astragalus 500g, notoginseng 500g;
[0018] (2), extraction process:
[0019] Ganoderma lucidum spores were pulverized with a high-speed pulverizer to obtain ganoderma lucidum spore powder with a wall-breaking rate of over 98%, dried to obtain ganoderma spore granules by wet granulation, and supercritically extracted at 60°C and 25Mpa for 2.5 hours to obtain a residue and Ganoderma lucidum spore essential oil; semi-bionic extraction of the residue obtained in the first step in water with a pH value of 6 at 40°C twice for 1.5 hours each time, filtering the extract, concentrating and drying the filtrate under reduced pressure to obtain an extract powder; Ginseng decoction pieces, Astragalus decoction pieces and Panax notoginseng decoction pieces are mixed, then heated and refluxed with 70vol% ethanol which is 5 times the weight of the medicinal materials, and extracted twic...
Embodiment 2
[0023] (1) Raw material ratio: Ganoderma lucidum spore powder 1100g, ginseng 1100g, rhodiola rosea 1100g, astragalus 550g, notoginseng 550g;
[0024] (2), extraction process:
[0025] Pulverize the spores of Zizhi lucidum with a high-speed pulverizer to obtain a powder of Ganoderma lucidum spores with a wall-breaking rate of over 98%, dry the spores of Ganoderma lucidum by wet granulation, and perform supercritical extraction at 60°C and 25Mpa for 2.5 hours to obtain a residue and Ganoderma lucidum spore essential oil; semi-bionic extraction of the residue obtained in the first step in water with a pH value of 6 at 40°C twice for 1.5 hours each time, filtering the extract, concentrating and drying the filtrate under reduced pressure to obtain an extract powder; Ginseng decoction pieces, Astragalus decoction pieces and Panax notoginseng decoction pieces are mixed, then heated and refluxed with 70vol% ethanol which is 5 times the weight of the medicinal materials, and extracted ...
Embodiment 3
[0029] (1) Raw material ratio: Ganoderma lucidum spore powder 900g, ginseng 900g, rhodiola rosea 900g, astragalus 450g, notoginseng 450g;
[0030] (2), extraction process:
[0031]Ganoderma lucidum spores were pulverized with a high-speed pulverizer to obtain ganoderma lucidum spore powder with a wall-breaking rate of over 98%, dried to obtain ganoderma spore granules by wet granulation, and supercritically extracted at 60°C and 25Mpa for 2.5 hours to obtain a residue and Ganoderma lucidum spore essential oil; semi-bionic extraction of the residue obtained in the first step in water with a pH value of 6 at 40°C twice for 1.5 hours each time, filtering the extract, concentrating and drying the filtrate under reduced pressure to obtain an extract powder; Ginseng decoction pieces, Astragalus decoction pieces and Panax notoginseng decoction pieces are mixed, then heated and refluxed with 70vol% ethanol which is 5 times the weight of the medicinal materials, and extracted twice for...
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