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Ganoderma Lucidum spore essential oil compound soft capsule preparation and preparation method thereof

A technology of soft capsule preparation and spore essential oil, which is applied in the fields of capsule delivery, anti-virus agents, and pharmaceutical formulas, etc., and can solve problems such as long-term delays, months or even years, heavy tasks, lack of anti-fatigue effects, etc. , to achieve high bioavailability, high extraction efficiency, and no excessive pesticide residues

Inactive Publication Date: 2010-10-27
NO 411 HOSPITAL OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Since the 20th century, although no major world wars have occurred in the world, wars in local areas have occurred frequently, such as in Iraq, Israel and other regions. Make various preparations for weapons, equipment, logistics support, medical and health care, etc. The time of war is tight, the tasks are heavy, the front line is long, and the delay can take months or even years. , it is a very important issue to make soldiers energetic, refreshed, and light in body, especially in a difficult environment for long-term combat
In short, there is a lack of preparations with significant anti-fatigue effects in the prior art, which are used to improve the combat effectiveness of troops in harsh environments such as high temperature, high cold, and hypoxia.

Method used

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  • Ganoderma Lucidum spore essential oil compound soft capsule preparation and preparation method thereof
  • Ganoderma Lucidum spore essential oil compound soft capsule preparation and preparation method thereof
  • Ganoderma Lucidum spore essential oil compound soft capsule preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0017] (1), raw material ratio: Ganoderma lucidum spore powder 1000g, ginseng 1000g, rhodiola rosea 1000g, astragalus 500g, notoginseng 500g;

[0018] (2), extraction process:

[0019] Ganoderma lucidum spores were pulverized with a high-speed pulverizer to obtain ganoderma lucidum spore powder with a wall-breaking rate of over 98%, dried to obtain ganoderma spore granules by wet granulation, and supercritically extracted at 60°C and 25Mpa for 2.5 hours to obtain a residue and Ganoderma lucidum spore essential oil; semi-bionic extraction of the residue obtained in the first step in water with a pH value of 6 at 40°C twice for 1.5 hours each time, filtering the extract, concentrating and drying the filtrate under reduced pressure to obtain an extract powder; Ginseng decoction pieces, Astragalus decoction pieces and Panax notoginseng decoction pieces are mixed, then heated and refluxed with 70vol% ethanol which is 5 times the weight of the medicinal materials, and extracted twic...

Embodiment 2

[0023] (1) Raw material ratio: Ganoderma lucidum spore powder 1100g, ginseng 1100g, rhodiola rosea 1100g, astragalus 550g, notoginseng 550g;

[0024] (2), extraction process:

[0025] Pulverize the spores of Zizhi lucidum with a high-speed pulverizer to obtain a powder of Ganoderma lucidum spores with a wall-breaking rate of over 98%, dry the spores of Ganoderma lucidum by wet granulation, and perform supercritical extraction at 60°C and 25Mpa for 2.5 hours to obtain a residue and Ganoderma lucidum spore essential oil; semi-bionic extraction of the residue obtained in the first step in water with a pH value of 6 at 40°C twice for 1.5 hours each time, filtering the extract, concentrating and drying the filtrate under reduced pressure to obtain an extract powder; Ginseng decoction pieces, Astragalus decoction pieces and Panax notoginseng decoction pieces are mixed, then heated and refluxed with 70vol% ethanol which is 5 times the weight of the medicinal materials, and extracted ...

Embodiment 3

[0029] (1) Raw material ratio: Ganoderma lucidum spore powder 900g, ginseng 900g, rhodiola rosea 900g, astragalus 450g, notoginseng 450g;

[0030] (2), extraction process:

[0031]Ganoderma lucidum spores were pulverized with a high-speed pulverizer to obtain ganoderma lucidum spore powder with a wall-breaking rate of over 98%, dried to obtain ganoderma spore granules by wet granulation, and supercritically extracted at 60°C and 25Mpa for 2.5 hours to obtain a residue and Ganoderma lucidum spore essential oil; semi-bionic extraction of the residue obtained in the first step in water with a pH value of 6 at 40°C twice for 1.5 hours each time, filtering the extract, concentrating and drying the filtrate under reduced pressure to obtain an extract powder; Ginseng decoction pieces, Astragalus decoction pieces and Panax notoginseng decoction pieces are mixed, then heated and refluxed with 70vol% ethanol which is 5 times the weight of the medicinal materials, and extracted twice for...

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Abstract

The invention relates to a Ganoderma Lucidum spore essential oil compound soft capsule preparation and a preparation method thereof. The Ganoderma Lucidum spore essential oil compound soft capsule preparation is characterized by being prepared from the following components in parts by weight: 900-1100 parts of Ganoderma Lucidum spore powder, 900-1100 parts of ginseng, 450-550 parts of astragalus mongholicus, 450-550 parts of pseudo-ginseng and 900-1100 parts of rhodiola rosea. The preparation method is characterized by comprising the following steps: crushing Ganoderma lucidum Karst or Ganoderma sinensis spores, pelletizing by a wet method, and extracting in a supercritical manner to obtain residue and Ganoderma Lucidum spore essential oil; performing semi-bionic extraction on the residue to obtain extractive powder; extracting the ginseng, astragalus mongholicus and pseudo-ginseng slices, filtering, concentrating under reduced pressure and drying filtrate to obtain extractive powder; and mixing the Ganoderma Lucidum spore essential oil and the extractive powder to prepare into soft capsules. The Ganoderma Lucidum spore essential oil compound soft capsule preparation has the advantage of remarkable effect of antifatigue.

Description

technical field [0001] The invention relates to a ganoderma spore essential oil compound soft capsule preparation and a preparation method thereof, which are used for anti-fatigue, anti-oxidation, anti-aging, anti-stress, significantly enhancing muscle strength and enhancing body resistance, and belong to the technical field of traditional Chinese medicine preparations. Background technique [0002] Since the 20th century, although no major world wars have occurred in the world, wars in local areas have occurred frequently, such as in Iraq, Israel and other regions. Make various preparations for weapons, equipment, logistics support, medical and health care, etc. The time of war is tight, the tasks are heavy, the front line is long, and the delay can take months or even years. Therefore, it is a very important topic to make soldiers energetic, refreshed, and light in body, especially in difficult environments for long-term combat. Therefore, there is a need for preparations...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61K9/48A61P37/04A61P39/06
Inventor 卞俊宣伟东鲍蕾蕾陈海飞王朝武袁兵孙艳曹尉尉柳正良沈丕安
Owner NO 411 HOSPITAL OF PLA
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