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Preparation method of DHA microemulsion

A microemulsion and co-emulsifier technology, applied in the field of health food preparation, can solve the problems of high process operating temperature, residual organic solvents, complicated preparation methods, etc., and achieve the effect of simple process, good high temperature stability and uniform distribution

Inactive Publication Date: 2011-02-16
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This background technology has the disadvantages of high process operating temperature, residual organic solvent, complicated preparation method and large particle size

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] DHA algae oil 0.1g, Tween80 0.85g, Span80 0.17g, n-butanol 0.2g, deionized water 2.2g. Take 0.1 g of DHA algae oil, 0.85 g of Tween80, 0.17 g of Span80, and 0.2 g of n-butanol in the same container, stir evenly under a magnetic stirrer, and add deionized water drop by drop at 30 ° C, while adding Stir and add 2.2 grams of deionized water to obtain a microemulsion.

Embodiment 2

[0015] DHA algae oil 0.5g, Tween80 2.85g, Span80 0.60g, PEG-400 1.14g, deionized water 4.65g. Take 0.5 grams of DHA algae oil, 2.85 grams of Tween80, 0.60 grams of Span80, and 1.14 grams of PEG-400 in the same container, stir evenly under a magnetic stirrer, and add deionized water drop by drop at 30 ° C, while adding Stir and add 4.65 grams of deionized water to obtain a microemulsion.

Embodiment 3

[0017] DHA algae oil 0.2g, EL-40 0.38g, Span80 0.13g, glycerin 0.5g, deionized water 1.55g. Take 0.2 grams of algae oil, 0.38 grams of EL-40, 0.13 grams of Span80, and 0.5 grams of glycerin in the same container, stir evenly under a magnetic stirrer, add deionized water drop by drop at 30°C, and stir while adding , Add 1.55 grams of deionized water to obtain microemulsion.

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PUM

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Abstract

The invention relates to a preparation method of a DHA microemulsion which comprises the following components in percent by mass of 2-20 percent of DHA algae oil, 0-5 percent of dispersing agent, 15-35 percent of compound emulsifying agent, 5-15 percent of assisting emulsifying agent and the balance of deionized water. The preparation method comprises the steps of: uniformly stirring the algae oil, the dispersing agent, the compound emulsifying agent and the assisting emulsifying agent by using a magnetic stirrer according to the proportion; slowly dropping the deionized water at a temperature of 25-80 DEG C under the stirring and regulating the optimal stirring speed with the generation of phase change to obtain the DHA microemulsion. The prepared DHA microemulsion has less consumption of the emulsifying agent, particle diameter of 43nm-50nm, loading rate of 2-20 percent and entrapment rate of 75 percent.

Description

technical field [0001] The invention relates to a method for preparing a new dosage form of a product containing DHA, and belongs to the field of health food preparation. Background technique [0002] DHA, or docosahexaenoic acid, is an essential polyunsaturated fatty acid for the human body. It is an important fatty acid component in the brain, nerves and visual cells. It plays an important role in the normal performance of human physiological functions and the prevention and treatment of various diseases. , especially plays a very important role in the development of infant brain and visual system. For adults, DHA is also an indispensable substance to maintain the normal function of the brain. A diet with low DHA content will accelerate the aging rate of the human body and easily lead to Alzheimer's disease. DHA can also prevent the occurrence of cardiovascular diseases, lower blood pressure, regulate the normal metabolism of blood lipids and lipoproteins in the human bo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L33/00
Inventor 肖小年易醒侯小晶刘媛洁胡少华曾海龙
Owner NANCHANG UNIV
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