Method for preparing medicinal preparation for treating cardiovascular and cerebrovascular diseases

A technology for cardiovascular and cerebrovascular diseases and pharmaceutical preparations, applied in the field of medicine, can solve problems such as large side effects, inability to stop bleeding, emboli blockage, etc., and achieve the effects of good bioavailability, reasonable preparation process and cost saving

Inactive Publication Date: 2011-02-16
彭军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Cardiovascular and cerebrovascular diseases are common and frequently-occurring diseases. Currently, there are many drugs for the treatment of cardiovascular and cerebrovascular diseases in clinical practice, such as western medicine dipyridamole and propranolol. The curative effect is outstanding, but after taking it, the side effects are large. In addition, some patients with cardiovascular and cerebrovascular diseases are treated with expansion method when the cardiovascular and cerebrovascular vessels cannot circulate normally, which will easily cause rupture of other blood vessels. , the blood vessel softening drugs can easily cause embolus blockage. Patients with cardiovascular and cerebrovascular diseases usually have both bleeding and embolism symptoms, and most patients have embolism and can cause bleeding. Disadvantages of not being able to thrombolyze

Method used

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  • Method for preparing medicinal preparation for treating cardiovascular and cerebrovascular diseases
  • Method for preparing medicinal preparation for treating cardiovascular and cerebrovascular diseases
  • Method for preparing medicinal preparation for treating cardiovascular and cerebrovascular diseases

Examples

Experimental program
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Effect test

Embodiment 1

[0050] Rhodiola rosea 300g, wolfberry fruit 200g, American ginseng 30g, salvia miltiorrhiza 100g, licorice 60g;

[0051] Said pharmaceutical preparation is prepared according to the following method:

[0052] (1) Rhodiola rosea was added with 60% ethanol of 6 times the amount of medicinal materials to carry out reflux extraction twice, each time for 1 hour, the ethanol extract was combined, the ethanol was recovered until it had no alcohol smell, and the extract was obtained;

[0053] (2) American ginseng is crushed into 80 mesh fine powder, set aside;

[0054] (3) Fructus wolfberry, salvia miltiorrhiza, and licorice were decocted twice with 4 times the amount of water, each time for 1 hour, and the decoctions were combined and concentrated into a clear paste with a relative density of 1.10 measured at 60°C;

[0055] (4) Combine (1) and (3) obtained ointment, concentrate under reduced pressure into a thick ointment whose relative density is 1.25 when measured at 60°C; add Ame...

Embodiment 2

[0058] Rhodiola rosea 800g, medlar 500g, American ginseng 80g, salvia miltiorrhiza 400g, licorice 120g;

[0059] Said pharmaceutical preparation is prepared according to the following method:

[0060] (1) Rhodiola rosea was added with 10 times the amount of 80% ethanol of the medicinal materials to carry out reflux extraction for 4 times, each time for 3 hours, the ethanol extract was combined, and the ethanol was recovered until there was no alcohol smell to obtain the extract;

[0061] (2) American ginseng is crushed into 100-mesh fine powder, and set aside;

[0062](3) Fructus wolfberry, salvia miltiorrhiza, and licorice were decocted with 6 times the amount of water for 4 times, each time for 3 hours, and the decoctions were combined and concentrated into a clear paste with a relative density of 1.10 measured at 60°C;

[0063] (4) Combine (1) and (3) obtained ointment, concentrate under reduced pressure into a thick ointment whose relative density is 1.25 when measured at...

Embodiment 3

[0066] Rhodiola rosea 500g, medlar 300g, American ginseng 50g, salvia miltiorrhiza 250g, licorice 80g;

[0067] Said pharmaceutical preparation is prepared according to the following method:

[0068] (1) Rhodiola rosea was added with 70% ethanol of 8 times the amount of medicinal materials to carry out reflux extraction for 3 times, each time for 2 hours, the ethanol extract was combined, and the ethanol was recovered until there was no alcohol smell to obtain the extract;

[0069] (2) American ginseng is crushed into 80-100 mesh fine powder, and set aside;

[0070] (3) Fructus wolfberry, salvia miltiorrhiza, and licorice were decocted with 5 times the amount of water for 3 times, each time for 2 hours, and the decoctions were combined and concentrated into a clear paste with a relative density of 1.10 when measured at 60°C;

[0071] (4) Combine (1) and (3) obtained ointment, concentrate under reduced pressure into a thick ointment whose relative density is 1.25 when measured...

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Abstract

The invention relates to a method for preparing a medicinal preparation for treating cardiovascular and cerebrovascular diseases, which comprises the following steps of: adding 60 to 80 percent ethanol in an amount which is 6 to 10 times that of rhodiola rosea serving as medicinal materials to perform reflux extraction for 2 to 4 times and 1 to 3 hours each time, merging ethanol extracting solution, recovering the ethanol until ethanol taste does not exist to obtain extract; pulverizing American ginseng to form 80 to 100-mesh fine powder for later use; decocting medlar, root of red-rooted salvia and liquoric root in water in an amount which is 4 to 6 times that of the mixture for 2 to 4 times and 1 to 3 hours each time, merging decoction, and concentrating (the measured relative density is 1.10 at the temperature of 60 DEG C); merging the extract, concentrating under reduced pressure to form thick paste with the measured relative density of 1.25 at the temperature of 60 DEG C; adding the American ginseng fine powder, and mixing uniformly; and adding a proper amount of auxiliary materials to prepare a clinically-applied liquid preparation. The medicinal preparation has a simple preparation method and high extraction ratio of active ingredients of the medicaments, does not need specific equipment, and reduces the production cost and the load of patients, and common production equipment can meet the requirements of producing the medicinal preparation.

Description

technical field [0001] The invention relates to a preparation method of a pharmaceutical preparation for treating cardiovascular and cerebrovascular diseases, belonging to the technical field of medicine. Background technique [0002] With the continuous improvement of people's living standards, cardiovascular and cerebrovascular diseases have become the second largest disease threatening human health after malignant tumors, and the incidence rate is increasing year by year. Cardiovascular and cerebrovascular diseases are common and frequently-occurring diseases. Currently, there are many drugs for the treatment of cardiovascular and cerebrovascular diseases in clinical practice, such as western medicine dipyridamole and propranolol. The curative effect is outstanding, but after taking it, the side effects are large. In addition, some patients with cardiovascular and cerebrovascular diseases are treated with expansion method when the cardiovascular and cerebrovascular vessel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P9/00A61K36/815
Inventor 彭军胡碧泉
Owner 彭军
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