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Thermally stable oil-in-water microemulsion

An oil-in-water and microemulsion technology, which is applied in skin care preparations, cosmetics, cosmetics, etc., can solve problems such as cumbersome, unfavorable practical preparations, and complex formulas

Inactive Publication Date: 2011-03-23
EVONIK DEGUSSA GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The formula of CN1751679A is complex and cumbersome, which is unfavorable for practical preparation

Method used

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  • Thermally stable oil-in-water microemulsion
  • Thermally stable oil-in-water microemulsion
  • Thermally stable oil-in-water microemulsion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] The formulation of Example 1 is shown in Table 1 below.

[0075] Table 1

[0076]

[0077] The components in the above Table 1 were stirred and mixed uniformly at 40°C, and then cooled to room temperature to obtain Product 1, which was completely transparent in appearance. The average particle diameter of product 1 measured by DELSA NANOS particle size distribution instrument of BECKMAN COULTER company is about 40nm, forming a microemulsion.

Embodiment 2

[0079] The formulation of Example 2 is shown in Table 2 below.

[0080] Table 2

[0081]

[0082]

[0083] The components in the above Table 2 were stirred and mixed uniformly at 40°C, and then cooled to room temperature to obtain product 2, which was completely transparent in appearance. The average particle diameter of product 2 measured by DELSA NANOS particle size distribution instrument of BECKMAN COULTER Company is about 89nm, forming a microemulsion.

Embodiment 3

[0085] The formulation of Example 3 is shown in Table 3 below.

[0086] table 3

[0087]

[0088] The components in the above Table 3 were stirred and mixed uniformly at 40°C, and then cooled to room temperature to obtain product 3, which was completely transparent in appearance. The average particle diameter of the product 3 measured by DELSA NANOS particle size distribution instrument of BECKMAN COULTER Company is about 80nm, forming a microemulsion.

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Abstract

The invention relates to oil-in-water microemulsion. The oil-in-water microemulsion comprises the following components based on the total weight: A) 75 to 94 weight percent of aqueous phase, B) 0.5 to 5 weight percent of oil phase, C) 2 to 20 weight percent of oil-in-water nonionic emulsifier serving as a surfactant, and D) 0.2 to 2 weight percent of auxiliary nonionic surfactant or auxiliary zwitterionic surfactant with the hydrophile-lipophile balance (HLB) value more than or equal to 17, wherein the weight ratio of the component C to the component D is 5 to 20. The oil-in-water microemulsion of the invention has thermal stability, can maintain the transparent property of the oil-in-water microemulsion at room temperature in the condition of high temperature, and has no phenomenon of turbidity, emulsion breaking or demixing; moreover, the microemulsion has a simple formula and is easy to prepare; in addition, the microemulsion can remove cosmetics rapidly, has a cleaning effect of being washed easily, also can be used as a resident product, and provides a moisture feeling different from a common water aqua product.

Description

technical field [0001] The invention relates to a thermally stable oil-in-water microemulsion. Background technique [0002] If two or more immiscible liquids are mixed and emulsified, and the average diameter of dispersed droplets or emulsified particles is between 5 and 100 nm, the system is called a microemulsion. Microemulsion is usually a system formed by mixing components such as water, oil, surfactant and co-surfactant, and the system is homogeneous on a macroscopic scale. Microemulsions are usually translucent to transparent due to the poor scattering ability of dispersed tiny droplets to light. A microemulsion whose dispersed phase is oil and whose dispersion medium is water is called an oil-in-water microemulsion, and vice versa is called a water-in-oil microemulsion. Thermodynamically, microemulsions are stable systems that can form spontaneously without special production equipment and processes. Microemulsion has unique appearance and special performance, and...

Claims

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Application Information

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IPC IPC(8): A61K8/90A61K8/92A61K8/89A61K8/891A61K8/894A61K8/86A61K8/06A61Q1/14A61Q19/00
Inventor 张海州戴静亚邹佳丽高志恒
Owner EVONIK DEGUSSA GMBH
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