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Medicament for preventing and treating acute myocardial infarction and cardiac failure and protecting cardiac functions and preparation method thereof

A technology for acute myocardial infarction and heart failure, which is applied in the field of preventing and treating acute myocardial infarction and heart failure and protecting heart function, can solve the problems of high mortality, and achieve the effects of low cost and simple production process.

Active Publication Date: 2013-02-13
吉林康乃尔药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although there are new western medicines used in the clinical treatment of cardiac insufficiency after acute myocardial infarction, they fail to achieve a truly satisfactory effect and the mortality rate remains high.

Method used

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  • Medicament for preventing and treating acute myocardial infarction and cardiac failure and protecting cardiac functions and preparation method thereof
  • Medicament for preventing and treating acute myocardial infarction and cardiac failure and protecting cardiac functions and preparation method thereof
  • Medicament for preventing and treating acute myocardial infarction and cardiac failure and protecting cardiac functions and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A medicine for preventing and treating acute myocardial infarction and heart failure and protecting heart function, which consists of the following raw materials in parts by weight: 18 parts of astragalus, 16 parts of Codonopsis pilosula, 13 parts of Polygonatum, 12 parts of Salvia miltiorrhiza, 9 parts of turmeric and 12 parts of red peony share.

[0028] The preparation method of this medicine comprises the following steps:

[0029] (1) Weigh Radix Astragali, Codonopsis Radix, Radix Polygonatum, Salvia Miltiorrhiza, Curcuma Radix and Radix Paeoniae Rubra, add 10 times the amount of water and decoct 3 times for 1.5 hours each time, filter and combine the filtrates;

[0030] (2) When the filtrate in the step (1) is concentrated to water as a reference density, the relative density is 1.15-1.20 thick paste at 60 DEG C. The conditions for vacuum concentration are: vacuum tightness 0.06kpa, temperature 60 DEG C; Spray drying, the process conditions of spray drying are: li...

Embodiment 2

[0034] A medicine for preventing and treating acute myocardial infarction and heart failure and protecting heart function, which is composed of the following raw materials in parts by weight: 22 parts of astragalus, 14 parts of Codonopsis pilosula, 17 parts of Polygonatum, 8 parts of Salvia miltiorrhiza, 11 parts of turmeric and 8 parts of red peony share.

[0035] All the other are with embodiment 1.

Embodiment 3

[0037] A medicine for preventing and treating acute myocardial infarction and heart failure and protecting heart function, which is composed of the following raw materials in parts by weight: 20 parts of astragalus, 15 parts of Codonopsis pilosula, 15 parts of Polygonatum, 10 parts of Salvia miltiorrhiza, 10 parts of turmeric and 10 parts of red peony share.

[0038] Made into granules. All the other are with embodiment 1.

[0039] According to the synthetic Chinese medicine of embodiment 3, the preparation technology of preparation and the research of quality control method have been carried out:

[0040] According to the provisions of the Drug Registration Law of the State Food and Drug Administration on traditional Chinese medicine, according to the research requirements of new drugs for the reform of traditional Chinese medicine formulations, on the basis of the analysis of the active ingredients of the drug, the preparation process of the preparation was optimized by usi...

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Abstract

The invention discloses a medicament for preventing and treating acute myocardial infarction and cardiac failure and protecting cardiac functions, which is prepared from the following raw materials in parts by weight: 18-22 parts of milk vetch, 14-16 parts of dangshen, 13-17 parts of sealwort, 8-12 parts of red sage root, 9-11 parts of radix curcumae and 8-12 parts of red peony root. The medicament disclosed by the invention has the advantages of simple preparation process and low cost, is completely prepared from natural plants, does not contain hormones, has no addition of pigments and other chemical synthetics, and does not have toxic side effects on human bodies after being used continuously. The traditional Chinese medicine contains various effective components such as saponin, flavone, polysaccharide, phenolic acid, alkaloid and the like which can be easily absorbed by human bodies, is suitable for treating qi deficiency and blood stasis type acute myocardial infarction in an adjuvant way, is suitable for treating cardiac failure, cardiac insufficiency and the like caused by acute myocardial infarction, and has the functions of supplementing qi, activating blood circulation, removing blood stasis and relieving pain.

Description

technical field [0001] The invention relates to a medicine for preventing and treating acute myocardial infarction and heart failure and protecting heart function and a preparation method thereof. Background technique [0002] Acute myocardial infarction belongs to the category of diseases such as "true pain", "jue heart pain" and "heart pain" in traditional Chinese medicine. Ancient medicine has accumulated rich experience in the etiology, pathogenesis, differentiation and treatment of "true pain". Once dead". Explain that "true pain" is not ordinary chest pain and heart pain, the condition is serious, and the prognosis is poor. Secondly, the word "true" is used to distinguish the pain caused by syndromes such as stomach, liver, and gallbladder near the heart. "Nanjing Sixty Difficulties" pointed out that "the pain is severe, but it is in the heart, and those with blue hands and feet are called real pain, and they will die sooner or later." Zhang Zhongjing's "Synopsis of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/04A61P9/10
Inventor 史大卓刘剑刚董国菊张蕾马鲁波
Owner 吉林康乃尔药业有限公司
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