Traditional Chinese medicinal nano-cream for treating chronic eczema

Abstract

The invention relates to traditional Chinese medicinal nano-cream for treating chronic eczema, which can effectively prevent the problem of curative effect reduction caused by gradually lowered concentration of medicines at parts with pathological changes. The cream is prepared from paeonol, matrine, oxymatrine, berberine hydrochloride, borneol, menthol, ethoxylated hydrogenated castor oil, isopropyl myristate (IPM), ethylparaben, sodium dodecyl sulfate (SDS), glycerin monostearate (GMS), white Vaseline, liquid paraffin, glycerin and single distilled water. The preparation process of the traditional Chinese medicinal nano-cream comprises the following steps: mixing the ethoxylated hydrogenated castor oil with the IPM, and then adding the paeonol, the matrine, the borneol and the menthol and dissolving into an oil phase; dissolving the berberine hydrochloride in the single distilled water and then adding the oxymatrine, adding into the oil phase, and performing ultrasonic treatment to obtain nanoemulsion; and mixing the SDS, the glycerin and the ethylparaben, heating and dissolving, and then adding into the nanoemulsion, adding the mixed nanoemulsion to fused solution of the GMS, the white Vaseline and the liquid paraffin, performing water bath, and condensing to finally obtain the traditional Chinese medicinal nano-cream. The obtained traditional Chinese medicinal nano-cream can be used for treating chronic eczema and has good curative effect.

Description

1. Technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine nano-cream (also known as eczema nano-cream) for treating chronic eczema. 2. Background technology [0002] Eczema (eczema) is a common and frequently-occurring disease in dermatology. It is clinically divided into three stages: acute, subacute and chronic eczema. Because eczema often recurs and turns into chronic, chronic eczema is the most common clinically. [0003] The treatment of chronic eczema in traditional Chinese medicine can use syndrome differentiation and treatment, Chinese patent medicine, unilateral prescription, external treatment, acupuncture and other treatments, and external treatment of drugs is one of the most effective means for treating chronic eczema. External treatment of drugs includes external washing and external application etc., the commonly used one is ointment. Regarding the use of traditional Chinese medicine ointment, th...

AI Technical Summary

Problems solved by technology

[0004] In response to the above situation, after a series of research, we have invented a traditional Chinese medicine nano-cream for the treatment of chronic eczema. This traditional Chinese medicine nano-cream can effectively solve the problems of traditional Chinese medicine ointments such as rough appearance, pigmentation, easy contamination of clothes, and poor patient compliance. At the same time, it can also prevent the gradual decrease of the drug concentration in the lesion due to the transdermal absorption of the drug, resulting in a decline in the curative effect.

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