Foot and mouth disease virus antigen polypeptide, fusion antigen polypeptide and vaccine

A technology of foot-and-mouth disease virus and antigenic polypeptide, which is applied in the direction of viral peptides, anti-viral agents, peptides, etc., can solve the problems of difficulty in prevention and control of foot-and-mouth disease and inability to immunize each other.
CN102180952AInactive Publication Date: 2011-09-14SHANGHAI SHEN LIAN BIOMEDICAL CORP
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI SHEN LIAN BIOMEDICAL CORP
Publication Date
2011-09-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a foot and mouth disease virus antigen polypeptide, a foot and mouth disease virus fusion antigen polypeptide and a foot and mouth disease virus vaccine containing the antigen polypeptide and / or the fusion antigen polypeptide. The invention further provides application of the antigen polypeptide, the fusion antigen polypeptide and the vaccine in prevention and control of foot and mouth disease virus infection. The foot and mouth disease virus antigen polypeptide, the fusion antigen polypeptide and the vaccine have broad-spectrum immunogenicity, and can generate good immunogenicity on different foot and mouth disease viruses and variant strains thereof.
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Description

technical field

[0001] The invention relates to a foot-and-mouth disease virus antigen polypeptide, a fusion antigen polypeptide, and a foot-and-mouth disease virus vaccine containing the above antigen polypeptide and / or fusion antigen polypeptide. The present invention also relates to the preparation and application of the above-mentioned antigen polypeptide, fusion antigen polypeptide and vaccine. Background technique

[0002] Foot-and-mouth disease is an acute, febrile, highly contagious zoonotic disease caused by foot-and-mouth disease virus. Foot-and-mouth disease mainly affects cloven-hoofed animals, and its clinical diagnosis is characterized by blisters on the oral mucosa, hooves and breast skin. Adult animals infected with foot-and-mouth disease generally have a low mortality rate, but the morbidity rate can reach 100%. A large number of blisters will appear on the mouth and hooves of infected animals, and the spirit will be depressed, which will lead to a sharp dr...

Claims

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