Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of beta-resorcylic acid large ring lactone in controlling harmful snails

A kind of technology of use and compound, applied in the field of β-resorcinolide macrolide

Active Publication Date: 2013-01-23
SOUTH CHINA BOTANICAL GARDEN CHINESE ACADEMY OF SCI
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there have been no reports on the use of the above β-resorcinolide macrolide for the prevention and control of harmful snails

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of beta-resorcylic acid large ring lactone in controlling harmful snails
  • Application of beta-resorcylic acid large ring lactone in controlling harmful snails
  • Application of beta-resorcylic acid large ring lactone in controlling harmful snails

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: the preparation of the compound represented by general formula (1) of the present invention

[0033] Paecilomyces sp.SC0924 CGMCC No.2900 strain was inoculated on 11.50 L of rice solid medium (rice and water at a mass ratio of 1:1), and cultured statically at 26° C. in the dark to obtain a solid fermentation culture. The obtained solid fermentation culture was extracted 3 times with 1.5 times the volume of 95% ethanol for 24 hours each time. After the ethanol aqueous solution was concentrated under reduced pressure to remove ethanol, it was extracted 3 times with an equal volume of chloroform, and the extract was concentrated to obtain a 97.50% chloroform extract. g.

[0034] The chloroform extract was subjected to silica gel column chromatography, and gradient elution was carried out with a mixed solvent of chloroform-methanol with a volume ratio of 100:0 to 80:20, and similar fractions were detected by thin-layer chromatography, and petroleum ether was c...

Embodiment 2

[0046] Embodiment 2: the molluscicidal activity of embodiment 1 compound

[0047] The oncomelania snails used in the experiment were provided by the Jingzhou Center for Disease Control and Prevention in Hubei Province, and the apple snails were collected from the farm of South China Agricultural University.

[0048] The test compound and the positive control tea saponin were dissolved with a small amount of acetone respectively, and diluted with dechlorinated tap water to 20mg / L, 10mg / L and 5mg / L (the final concentration of acetone was less than 0.5% by volume) for the test solution.

[0049] Add 20mL of the above-mentioned different concentrations of the test solution and blank control (dechlorinated tap water with 0.5% acetone added) into a 50mL beaker, put 10 snails in each beaker, and incubate at room temperature (26 ° C ± 1 ° C), respectively, with 48 h and 10 snails. 78h observed the death of Oncomelania snails and apple snails. Observe its activity by tapping method to...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of beta-resorcylic acid large ring lactone expressed through the following general formula (1) in the specification to controlling harmful snails. An indoor molluscicidal drug soaking activity evaluation test indicates that four compounds expressed through the general formula (1) have good molluscicidal activities, wherein when the four compounds are used under the concentration of 10 mg / L for 72 hours, Monocillin II can achieve the molluscicidal rate of more than 95 percent on oncomelania and the molluscicidal rate of more than 70 percent on ampullaria gigas; Radicicol can achieve the molluscicidal rate of more than 75 percent on the oncomelania and the eradicative rate of more than 90 percent on the ampullaria gigas; Monocillin I can achieve the molluscicidal rate of more than 40 percent on the ampullaria gigas; and Monocillin III can achieve the molluscicidal rate of more than 70 percent on the ampullaria gigas.

Description

technical field [0001] The invention relates to a new application of β-resorcinol macrolide, in particular to a new application of β-resorcinolide in the prevention and treatment of harmful snails. Background technique [0002] Snails are a general term for mollusk gastropods, with a wide variety and wide distribution. Many of them can be eaten by people, such as Chinese round snails and square ring or rib snails, or used as feed or bait, such as ear river snails and Big marsh snail, etc. But there are also many snails that are the intermediate hosts of various human or livestock parasites. For example, oncomelania is the intermediate host of Schistosoma japonicum; The intermediate host of fasciola, the round flat snail is the intermediate host of fasciola brucei, etc. Once they are infected, their reproduction and spread will seriously endanger people's health. In addition, there are some snails, such as apple snails, which can reproduce rapidly and excessively, seriously...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/90A01N43/22A01P9/00C12P17/08C12P17/18C12R1/79
Inventor 徐良雄魏孝义薛璟花吴萍游晓莹
Owner SOUTH CHINA BOTANICAL GARDEN CHINESE ACADEMY OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com