Long-chain alkyl salicylic compound as well as preparation method application thereof

A chain alkyl salicylic acid and alkyl salicylic acid technology, which is applied in the compound synthesis and pesticide fields, can solve the problems of target biological drug resistance increase, environmental pollution, use restriction, etc., and achieve a simple synthesis method, easy promotion, and low cost of use Effect
CN102010328AInactive Publication Date: 2011-04-13FUDAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FUDAN UNIV
Publication Date
2011-04-13
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the fields of compound synthesis and pesticides, in particular to a long-chain alkyl salicylic compound as well as a preparation method and application thereof in molluscicide preparation. Easily obtained raw materials and a simple synthetic method with low cost are adopted in the invention to synthesize the target compound. Proved by molluscicide test and shown by results, the LC50 value of the synthetic compound for killing oncomelania is within the oncomelania-killing activity range (smaller than 400 mg / L) of the molluscicide, which is required by the WTO (World Trade Organization). The compound of the invention can be singly used as the molluscicide or be used together with other molluscicides, can be further compounded with different accessories to prepare microemulsion, emulsion, powder and water agent or compounded with niclosamide, copper ion and other accessories to prepare a composite molluscicides to enhance the oncomelania killing effect, lessen the toxic and side effects and decrease the cost.
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Description

technical field

[0001] The invention belongs to the field of compound synthesis and pesticides, and relates to a hydrocarbyl salicylic acid compound, a preparation method thereof and an application in preparation of oncomelania preparations. Background technique

[0002] The prior art discloses that oncomelania is the only intermediate host for the transmission of schistosomiasis. The miracidia of schistosomiasis can develop into schistosomiasis after invading the snail, which multiplies tens of thousands of times in the snail, and continuously produces cercariae in the water or on the wet soil surface, so as to infect humans and other animals. The spread and spread of the disease. Epidemiology believes that eradicating snails can cut off the transmission route of schistosomiasis. Therefore, killing snails is an internationally recognized important measure to prevent schistosomiasis.

[0003] Surveys show that schistosomiasis is prevalent in temperate, subtropical, and tr...

Claims

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