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Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome

A polycystic ovary and composition technology is applied in the directions of drug combination, arthropod-derived medical raw materials, and pharmaceutical formulations, which can solve problems such as ovarian damage, low pregnancy rate, high abortion rate, etc. Effects of ovulation rate and pregnancy rate, growth and development improvement

Active Publication Date: 2012-01-04
上海泰坤堂中医医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs not only cannot effectively treat all PCOS, but also have defects such as low pregnancy rate and high miscarriage rate
Surgical puncture techniques are also used in the treatment of PCOS, which may cause damage to the ovaries, or cause pelvic adhesions and potential harm to the fetus

Method used

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  • Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome
  • Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome
  • Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The preparation of embodiment 1 decoction

[0036] Take 0.6g of hippocampus, 15g of fairy spleen, 12g of fritillaria, 15g of psoralen, 12g of tortoise shell, 12g of antler slices, 15g of saponin thorn and 15g of calamus, rinse with water, soak in the container for more than 2 hours, and then fry And the following traditional decocting process, decocting at normal pressure for 20 minutes to filter out the medicinal liquid.

Embodiment 2

[0037] The preparation of embodiment 2 ointment

[0038] Take 6g of hippocampus, 150g of fairy spleen, 120g of fritillaria, 150g of psoralen, 120g of tortoise shell, 120g of antler slices, 150g of saponin thorn and 150g of calamus, rinse with water, soak in the container for more than 2 hours, and then fry and mix The following traditional decoction process, after decocting under normal pressure, filter out the liquid medicine and concentrate the liquid medicine under reduced pressure. During the concentration process of the liquid medicine, add rock sugar, maltose and rice wine and other required sugars and necessary auxiliary materials, and stir to collect the paste .

Embodiment 3

[0039] Embodiment 3 clinical observation

[0040] Patients with kidney yang deficiency and phlegm obstruction were included according to the following criteria:

[0041] A) Diagnostic criteria of Western medicine: 1) Menstrual cramps for more than 2 years are still anovulatory menstruation (BBT monophasic), oligomenorrhea or amenorrhea; 2) Blood androgen rise: on the third day of uterine bleeding, blood testosterone (T) rises High or log testosterone / estradiol ratio (logT / E 2 ) > 0.97; 17α-hydroxyprogesterone (17α-OHP) and androstenedione may be combined; 3) B-ultrasound examination found that the ovarian volume increased (≥ 6ml), and the number of follicles with a diameter of 2-9mm on a plane in the cortex >10.

[0042] B) Standards of TCM syndrome differentiation: dry mouth, low back pain, fatigue, fear of cold and cold abdomen, less leucorrhea, excessive phlegm and body weight, dark tongue, thin and greasy tongue coating, thready or slippery pulse.

[0043] Adopt Chinese...

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PUM

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Abstract

The invention relates to a Chinese medicinal composition for a kidney-yang deficiency and phlegm-retention type polycystic ovary syndrome. The Chinese medicinal composition comprises the following medicinal materials of epimedium, caladium, semen psoraleae, sliced deerhorn, sea horse, tortoise plastron and the like, does not contain rhubarb and Chinese angelica. The Chinese medicinal composition can reduce the level of androgens and androgen receptors of polycystic ovanian syndrome (PCOS) patients, improve the level of sex hormone binding globulin, reduce the level of free testosterone, improve the level of in-vivo estrogens, improve the growth and development of follicles and improve the ovulation rate and pregnancy rate of patients.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating polycystic ovary syndrome, in particular to a medicinal composition composed of various Chinese medicinal materials according to the phases of monarch, minister, adjuvant and envoy, which is used for kidney-yang deficiency and phlegm obstruction Traditional Chinese medicine composition for polycystic ovary syndrome. Background technique [0002] Polycystic ovary syndrome (Polycystic Ovary Syndrome, PCOS) was proposed by Stein and Leventhal in 1935. A type of disease manifested. This disease is a common endocrine disease in women and mostly causes reproductive disorders, and its incidence rate accounts for 5%-10% of women of childbearing age. Studies in recent years have widely recognized that women with PCOS have different degrees of insulin resistance, and insulin resistance accompanied by hyperinsulinemia can cause many clinical symptoms, such as: excessive androgen le...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K36/9066A61K36/90A61K36/902A61K36/9064A61K36/899A61P15/00A61K35/56A61K35/32A61K33/26A61K35/62A61K35/64A61K35/586A61K35/60
Inventor 俞谨潘芳武大圣
Owner 上海泰坤堂中医医院有限公司
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