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Traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and method for preparing traditional Chinese medicine preparations

A technology of qi and blood deficiency and traditional Chinese medicine preparations, which is applied in the direction of drug combinations, medical formulas, and medical preparations containing active ingredients, etc., can solve the problem that leukemia patients cannot fundamentally get rid of leukemia, the survival rate of leukemia patients is low, and the survival rate of leukemia patients is low. low level problem

Active Publication Date: 2013-06-12
XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI
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Problems solved by technology

In the prior art, there are following technical defects in the traditional Chinese medicine medicine used for treating leukemia patients with deficiency of Qi and blood after chemotherapy: 1. The survival rate of leukemia patients is relatively low: the 5-year survival rate of Chinese children with AML is about 20% to 30%. The overall survival rate of children with leukemia in China is about 50%; the survival rate of adult AML is about 10% to 35%, and the overall survival rate of adult leukemia is about 10% to 30%; The rate can reach 40% to 50%; although there is a certain gap in the data reported by various literatures, it is an indisputable fact that the survival rate of leukemia patients is low
2. There is no effective traditional Chinese medicine for the treatment of minimal residual leukemia, so that leukemia patients cannot fundamentally get rid of the torture of leukemia; especially for minimal residual leukemia after treatment of acute myeloid leukemia, if the patient can be completely relieved, it will be It can prevent or delay the recurrence of acute myeloid leukemia on the basis of the current complete remission rate of 60% to 90%, thereby prolonging the survival period of patients

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  • Traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and method for preparing traditional Chinese medicine preparations
  • Traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and method for preparing traditional Chinese medicine preparations
  • Traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and method for preparing traditional Chinese medicine preparations

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Embodiment Construction

[0012] For further objectively evaluating the effect of Chinese medicine preparation of the present invention, clinical trial has been carried out, and by Chinese Academy of Chinese Medical Sciences Liangyuan Hospital, Shijiazhuang Ping An Hospital, Shandong University of Traditional Chinese Medicine Affiliated Hospital, North China Coal Medical College Affiliated Hospital, Chinese People's Liberation Army No. 210 Hospital (Dalian ), the First Affiliated Hospital of Zhengzhou University School of Medicine, Langfang Hospital of Traditional Chinese Medicine and other 7 tertiary medical units jointly completed 78 cases of clinical trials.

[0013] Clinical Trial 1: Clinical Research on the Treatment of Myeloid Minimal Residual Leukemia Using the Traditional Chinese Medicine of the Present Invention

[0014] 1. Research proposal

[0015] 1.1 Diagnostic criteria

[0016] According to Zhang Zhinan's "Diagnosis and Curative Effect Standards for Hematological Diseases", after acute l...

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Abstract

The invention discloses traditional Chinese medicine for treating qi and blood insufficiency asthenia diseases of leukemia patients after chemotherapy and a method for preparing traditional Chinese medicine preparations. The traditional Chinese medicine comprises the following raw materials in part by weight: 1 to 98 parts of astragalus mongholicus, 1 to 50 parts of red ginseng, 1 to 98 parts of bighead atractylodes rhizome, 1 to 98 parts of Tuckahoe, 1 to 100 parts of glossy privet fruit, 1 to 100 parts of ophiopogon root, 1 to 100 parts of dried rhizome of rehmannia, 1 to 100 parts of fructus psoraleae, 1 to 98 parts of fleece-flower root, 1 to 98 parts of epimedium and 1 to 98 parts of radix asparagi. The preparation method comprises the following steps of: (1) weighing and taking raw materials; (2) taking the red ginseng, adding ethanol for refluxing extraction twice, filtering the liquid and merging filter liquid, wherein the time of each extraction is 2 hours; and taking red ginseng medicine dregs obtained during filtering to be mixed with rest raw materials, adding water for soaking the medicine materials to be decocted twice, filtering the liquid and merging the decocting liquid, wherein the first decoction time is 2 hours, and the second decoction time is 1.5 hours; and (3) mixing the merged filter liquid and the merged decoction liquid. The traditional Chinese medicine has the advantages that the immunity of patients can be improved, the leukemia recrudescence is prevented or delayed, the life period is prolonged, and the life quality of the patients is improved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for leukemia patients and a preparation method of the traditional Chinese medicine preparation, in particular to a traditional Chinese medicine and a preparation method of the traditional Chinese medicine preparation for treating leukemia patients with deficiency of Qi and blood after chemotherapy. Background technique [0002] Most acute leukemia patients are in the state of minimal residual leukemia after chemotherapy. Minimal residual leukemia (MRL) is a state in which a small amount of leukemia cells remain in the body after leukemia treatment, and is the root cause of leukemia recurrence. So far, there are no diagnostic criteria for MRL at home and abroad. It is generally believed that MRL cells account for less than 1 / 1000-1 / 10000 of the total number of bone marrow cells, and cannot be detected by conventional cell morphology. Common detection methods include polymerase chain reaction (PCR)...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P1/14A61P37/04
Inventor 麻柔许勇钢
Owner XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI