Liposome composition

A liposome composition and liposome technology, applied in the direction of liposome delivery, drug combination, inorganic non-effective ingredients, etc., can solve the leakage of active compounds, the low stability of active compounds, and the difficulty of achieving high active compounds at the same time The encapsulation rate of active compounds maintains stability and other issues, and achieves the effect of maintaining high stability and high efficiency
CN102369008AActive Publication Date: 2012-03-07EISIA R&D MANAGEMENT CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
EISIA R&D MANAGEMENT CO LTD
Publication Date
2012-03-07

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Abstract

The present invention provides a novel liposome composition containing eribulin or its pharmacologically permissible salt, and its method of manufacture.
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Description

technical field

[0001] The present invention relates to a new liposome composition containing eribulin or its pharmacologically acceptable salt. In addition, the present invention relates to a method for producing the liposome composition. Background technique

[0002] Liposomes are tiny closed vesicles that have an inner phase surrounded by one or more lipid bilayers, capable of retaining water-soluble substances in the inner phase and fat-soluble substances in the lipid layer. In a double layer. When encapsulating active compounds in liposomes and delivering them to target tissues, how to encapsulate active compounds in liposomes efficiently and how to ensure the stability of active compounds using liposomes becomes important. topic.

[0003] When encapsulating fat-soluble compounds in liposomes, high encapsulation efficiency can be achieved relatively easily, but compounds with very high membrane affinity except amphotericin B (the main drug of liposome drug AmBisome) ...

Claims

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