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Anti-bacterial agents for treating childhood infections and infectious diseases and preparing method thereof

A technology for infectious diseases and antibacterial drugs, which is applied in the field of antibacterial drugs for the treatment of infectious diseases and infectious diseases in children and their preparation, and can solve problems such as bacterial resistance and antibiotic abuse.

Inactive Publication Date: 2012-03-21
山西皇城相府药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antibiotics have played an important role in the control or elimination of many infectious diseases and infectious diseases, but at the same time, the abuse of antibiotics and bacterial resistance have also occurred

Method used

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  • Anti-bacterial agents for treating childhood infections and infectious diseases and preparing method thereof
  • Anti-bacterial agents for treating childhood infections and infectious diseases and preparing method thereof
  • Anti-bacterial agents for treating childhood infections and infectious diseases and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] Weigh the raw materials according to the following ratio:

[0093] erythromycin ethylsuccinate 130g, sucrose powder 600g, sodium alginate 50g, stevia 9g, hydroxypropyl cellulose 20g, sodium lauryl sulfate 2g, tartrazine 7g, orange flavor 5g, sodium carboxymethyl starch 5g .

[0094] Specific preparation method:

[0095] 1) First, erythromycin ethylsuccinate, sucrose powder, and stevia are sieved and mixed evenly, and then sodium alginate, hydroxypropyl cellulose, sodium lauryl sulfate, tartrazine, and sodium carboxymethyl starch are added in sequence , mix well and pulverize into fine powder for later use;

[0096] 2), adding an appropriate amount of dilute ethanol solution to the fine powder obtained in step 1), and after fully stirring, a soft material is obtained, and then wet particles are obtained with a 30-mesh sieve;

[0097] 3) Then dry the wet granules at 45°C, sieve through a 30-mesh sieve, add orange flavor, mix well, pack them into packages, and make a dr...

Embodiment 2

[0099] Weigh the raw materials according to the following ratio:

[0100] erythromycin ethylsuccinate 130g, sucrose powder 400g, sodium alginate 30g, stevia 5g, hydroxypropyl cellulose 10g, sodium lauryl sulfate 1g, tartrazine 6g, orange flavor 4g, sodium carboxymethyl starch 4g .

[0101] Specific preparation method:

[0102] 1) First, erythromycin ethylsuccinate, sucrose powder, and stevia are sieved and mixed evenly, and then sodium alginate, hydroxypropyl cellulose, sodium lauryl sulfate, tartrazine, and sodium carboxymethyl starch are added in sequence , mix well and pulverize into fine powder for later use;

[0103] 2), adding an appropriate amount of dilute ethanol solution to the fine powder obtained in step 1), and after fully stirring, a soft material is obtained, and then wet particles are obtained with a 30-mesh sieve;

[0104] 3) Then dry the wet granules at 45°C, sieve through a 30-mesh sieve, add orange flavor, mix well, pack them into packages, and make a dr...

Embodiment 3

[0106] Weigh the raw materials according to the following ratio:

[0107] Erythromycin ethylsuccinate 125g, sucrose powder 800g, sodium alginate 60g, stevia 15g, hydroxypropyl cellulose 30g, sodium lauryl sulfate 5g, tartrazine 10g, orange flavor 8g, sodium carboxymethyl starch 8g .

[0108] Specific preparation method:

[0109] 1) First, erythromycin ethylsuccinate, sucrose powder, and stevia are sieved and mixed evenly, and then sodium alginate, hydroxypropyl cellulose, sodium lauryl sulfate, tartrazine, and sodium carboxymethyl starch are added in sequence , mix well and pulverize into fine powder for later use;

[0110] 2), adding an appropriate amount of dilute ethanol solution to the fine powder obtained in step 1), and after fully stirring, a soft material is obtained, and then wet particles are obtained with a 30-mesh sieve;

[0111] 3) Then dry the wet granules at 45°C, sieve through a 30-mesh sieve, add orange flavor, mix well, pack them into packages, and make a ...

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Abstract

The invention relates to anti-bacterial agents for treating childhood infections and infectious diseases, which adopt erythromycin ethylsuccinate, sucrose powder, sodium alginate, steviosin, hydroxy propyl cellulose, sodium lauryl sulphate, tartrazine, orange essence and sodium carboxymethyl starch as raw materials. The preparation method comprises the following steps: 1) firstly screening the erythromycin ethylsuccinate, the sucrose powder and the steviosin, then mixing uniformly, later adding the sodium alginate, the hydroxy propyl cellulose, the sodium lauryl sulphate, the tartrazine and the sodium carboxymethyl starch in turn, then uniformly mixing and crushing as fine powder for further use; 2) adding the fine power obtained in the step 1) to a right amount of dilute ethanol liquor, then fully stirring to obtain soft material, and screening by a 30 meshes sieve to obtain wet particles; 3) drying the wet particles at 45 degrees centigrade, pelletizing by the 30 meshes sieve, adding the orange essence, uniformly mixing and packaging to prepare the dry suspension. The invention has unified specification, easily grasps the dosage, dose not limit the water quantity, can be conveniently carried and used, can be applied to children tastes and has obvious curative effects.

Description

technical field [0001] The invention relates to a medicine, in particular to an antibacterial medicine prepared from chemical medicine as a raw material for treating infectious diseases and infectious diseases in children and a preparation method thereof. Background technique [0002] The development and production of children-specific drugs has always been called upon and valued by the medical community in my country, but children-specific drugs, especially oral drugs, still cannot meet the clinical application and needs. For the application of antibacterial drugs, there are even fewer dosages and specifications for children, as well as varieties suitable for children's tastes. Antibiotics have played an important role in the control or elimination of many infectious diseases and infectious diseases, but at the same time, the abuse of antibiotics and bacterial resistance have also occurred. When antibiotics must be used in children, it is best to follow the following princ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K9/16A61P31/04
Inventor 张建国
Owner 山西皇城相府药业股份有限公司
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