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51 results about "Sodium lauryl sulphate" patented technology

Arbidol dry suspension and preparation method thereof

The invention discloses an arbidol dry suspension and a preparation method thereof, and belongs to the medical industry. The arbidol dry suspension comprises Arbidol hydrochloride, a suspending aid, a diluent, a lubricating agent, a flavoring agent and a pH regulator, wherein the suspending aid is one or more of Arabic gum, tragacanth, sodium alga acid, povidone, hydroxy propyl cellulose and xanthan gum; the diluent is saccharose, mannitol and microcrystalline cellulose; the lubricating agent is lauryl sodium sulfate and sodium lauryl sulphate; the flavoring agent comprises a sweetener and an aromatizer, the sweetener is mannitol, saccharose, sodium cyclamate and aspartame, and the aromatizer is orange essence, banana essence, strawberry essence, and pineapple essence; and the pH regulator is citric acid and tartaric acid. The preparation method comprises the following steps of: sieving the arbidol hydrochloride, and respectively crushing and sieving the suspending aid, the diluent, and the lubricating agent; fully mixing the components except the diluent, and then adding the diluent for uniform mixing; and wetting by using ethanol to prepare a soft material, drying, and packaging into an aluminum-plastic composite membrane bag. After the arbidol is prepared into the dry suspension, the bitter of the arbidol is effectively masked, and the compliance of the patient is greatly improved.
Owner:SHENYANG NO 1 PHARMA FACTORY DONGBEI PHARMA GRP

Mouth spray for preventing and treating nausea and emesis after tumor chemotherapy and radiotheraphy and preparation method thereof

The invention relates to an oral spray for controlling nausea and vomit of chemotherapy and radiation therapy, the formula of the oral spray is composed of ingredients with the following parts by weight: 5-50 parts of drug absorption enhancer, 2-20 parts of drug active ingredient and 30-90 parts of buffer, the drug absorption enhancer can be any one or the combination of more of the following ingredients: azone, propylene glycol, polysorbate (Tween), ethylene glycol deoxycholic acid sodium salt, brij, sodium decanoate, lauric acid, stearic acid, sodium lauryl sulphate, stearyl alcohol sodium sulfate, dioctyl succinate sodium sulfonate, oleic acid, GK2, menthol and borneol; the drug active ingredient can be any one combination of the following ingredients: palonosetron hydrochloride, granisetron, ondansetron, azasetron and tropisetron; and the ingredients of the buffer are sodium citrate buffer solution and phosphate buffer solution. The oral spray provides a formulation which is safer, painless and convenient for patients with advanced tumor, elderly and weak patients, children patients and the patients who suffer from the metal illness and do not obey the oral administration or the injection drug administration.
Owner:陆飚 +1

Compound antioxidant for producing copper powder through water atomization method

ActiveCN104525959AImprove antioxidant capacityAddressing Higher Oxygen IssuesAntioxidantBenzotriazole
The invention discloses a compound antioxidant for producing copper powder through a water atomization method. The compound antioxidant comprises, by weight, 1-10 parts of benzotriazole, 1-10 parts of benzene sulfonic acid sodium salt, 1-10 parts of sodium lauryl sulphate, 2-10 parts of OP surfactants, 3-25 parts of glycerinum and 20-50 parts of water. According to the compound antioxidant for producing the copper powder through the water atomization method, by means of the component formula, the matching ration is reasonable, in the process of preparing the copper powder through the water atomization method, the free radical is complemented while film forming is conducted on the surface of the copper powder, the double-protection function is achieved, the good antioxidant effect is achieved, the antioxidant ability of the copper powder is improved effectively, and the problem that the oxygen content of copper power produced in a water atomization mode is higher is solved; in the process that the copper power is produced through the water atomization method, the antioxidant is added, the oxygen content of the copper powder produced through the water atomization method is lower than 0.08%, the oxygen content meets the national standard, the problem that the oxygen content of the copper powder obtained after water atomization is conducted is higher is solved, and the shelf life of the copper powder is prolonged.
Owner:佛山市顺德区美硕金属表面技术有限公司

Production method of PLA foam sheet

The invention provides a production method of a PLA (polylactic acid) foamed sheet, and the production method comprises the following steps of: pouring mixture formed by mixing 2-4% of nucleating agent, 1-3% of compound heat stabilizer, 0.3-0.5% of lubricating agent, 0.6-1% of dispersant and 1-4% of chain extender in mass ratio into 78.5-85.1% of a PLA material, mixing to be uniform, and conveying and melting by virtue of an extruder, wherein the nucleating agent is 3000-mesh talcum powder, the compound heat stabilizer is formed by mixing 80% of zinc stearate and 20% of calcium stearate in mass ratio, the lubricating agent is monoglyceride, the dispersant is sodium lauryl sulphate, and the chain extender is glycerine; then injecting 9% of butane with the purity of more than 98% at the pressure of 10-15 MPa to form a mixture at the temperature controlled to be 100-200 DEG C, and conveying the mixture to a moulding nose after being pressurized, mixed and cooled by virtue of a screw so as to be moulded into a foamed product. According to the invention, the PLA foamed sheet can be stably and reliably produced, the produced product has high foam density, small foam size, light mass and easiness in moulding, can substitute for most packaging material for food on the market and can be biologically degraded in nature, thus white pollution caused by the traditional macromolecule waste material to the environment can be greatly alleviated.
Owner:张建群

Anti-bacterial agents for treating childhood infections and infectious diseases and preparing method thereof

The invention relates to anti-bacterial agents for treating childhood infections and infectious diseases, which adopt erythromycin ethylsuccinate, sucrose powder, sodium alginate, steviosin, hydroxy propyl cellulose, sodium lauryl sulphate, tartrazine, orange essence and sodium carboxymethyl starch as raw materials. The preparation method comprises the following steps: 1) firstly screening the erythromycin ethylsuccinate, the sucrose powder and the steviosin, then mixing uniformly, later adding the sodium alginate, the hydroxy propyl cellulose, the sodium lauryl sulphate, the tartrazine and the sodium carboxymethyl starch in turn, then uniformly mixing and crushing as fine powder for further use; 2) adding the fine power obtained in the step 1) to a right amount of dilute ethanol liquor, then fully stirring to obtain soft material, and screening by a 30 meshes sieve to obtain wet particles; 3) drying the wet particles at 45 degrees centigrade, pelletizing by the 30 meshes sieve, adding the orange essence, uniformly mixing and packaging to prepare the dry suspension. The invention has unified specification, easily grasps the dosage, dose not limit the water quantity, can be conveniently carried and used, can be applied to children tastes and has obvious curative effects.
Owner:山西皇城相府药业股份有限公司

Externally applied emplastrum for treating anxious chronic bronchitis and preparation method thereof

The invention relates to an externally applied emplastrum for treating anxious chronic bronchitis and a preparation method thereof and belongs to the technical field of externally applied medical emplastrum. The preparation method thereof comprises the following steps of: extracting the ephedra, asarum, pinellia ternate, rhizoma arisaematis, fructus gleditsiae, rhizoma dioscoreae nipponicae, grass leaf sweetflag rhizome, blackberry lily, scutellaria baicalensis and platycodon grandiflorum by refluxing ethanol, reducing pressure and recovering the ethanol, concentrating the extracted solution into extractum, mixing the extractum with the aqueous phase solution prepared from stearic acid, solid paraffin, wool oil and ethyl p-hydroxybenzoate and the oil phase solution prepared from glycerol, sodium lauryl sulphate and triethanolamine so as to form ointment, and then paving on a frame. The medicine can quickly permeate into pained part through the conduction of acupuncture point and meridians and collaterals and the percutaneous absorption, so as to get through the Ren and Du meridians, relieve cough and asthma and regulate qi-flowing for eliminating phlegm. The invention solves the problems that the western medicine cures the symptoms but not root causes by using, the treatment limitation is big, the orally-taken dosage for Chinese traditional treatment is big, the taking is inconvenient and the curative effect is slow. The emplastrum of the invention is convenient to use, has good curative effect, becomes effective quickly, is free from side effect and is fit for both children and adults.
Owner:杨福海

Boron nitride/silica powder compounded ceramic nozzle and production method thereof

The invention discloses a boron nitride/silica powder compounded ceramic nozzle. The boron nitride/silica powder compounded ceramic nozzle is characterized by being prepared from the following raw materials in parts by weight: 70-80 parts of boron nitride, 3-6 parts of potassium feldspar, 4.1-5.6 parts of calcite, 7-12 parts of radium stone, 6-9 parts of blast furnace slag, 20-35 parts of ultrafine high-purity alumina powder, 1-2 parts of silica powder, 1.2-2.6 parts of polyacrylonitrile fibres, 0.6-0.9 part of sodium lauryl sulphate, 0.2-0.4 part of manganese sulphate, 0.5-1.1 parts of calcium carbonate, 6-9 parts of methyl methacrylate, 4-7 parts of dibutyl phthalate, 3-4 parts of ethyl alcohol, 2-4 parts of auxiliaries and an appropriate amount of water. According to the boron nitride/silica powder compounded ceramic nozzle disclosed by the invention, boron nitride and silica powder and compositely added to raw materials, meanwhile, blast furnace slag, radium stone and the like are further added, thus wastes are effectively utilized, cost is saved, and the performance indexes of the product are improved; the ceramic nozzle prepared by the method disclosed by the invention is good in chemical resistance, good in wear resistance, anti-corrosion at a high temperature, and capable of completely meeting the performance requirements of ceramic nozzles.
Owner:乌海市以诺实业有限责任公司

Novel pharmaceutical modified release dosage form composition comprising cyclooxygenase enzyme inhibitor

Pharmaceutical modified release dosage form comprising at least one cyclooxygenase enzyme inhibitor or its pharmaceutically acceptable salts, esters, prodrugs, solvates, hydrates, or derivatives thereof as active agent, with a pharmaceutically acceptable carrier for controlling the release of the cyclooxygenase enzyme inhibitor is provided. The dosage form preferably provides a release of not more than about 60 % of the cyclooxygenase enzyme inhibitor in 1 hour and not less than about 75 % of the cyclooxygenase enzyme inhibitor after 12 hours when tested in accordance with the dissolution method (I) described herein employing Distilled water with 2.0 % Sodium lauryl sulphate as the dissolution medium or in accordance with the dissolution method (II) described herein employing pH 7.0 Phosphate buffer with 2.0% Sodium lauryl sulphate as the dissolution medium or in accordance with the dissolution method (III) described herein employing 0.001 N Hydrochloric acid with 1.0 % Sodium lauryl sulphate as dissolution medium. Further, the pharmaceutical composition of the present invention when tested in a group of healthy humans preferably achieves a mean peak plasma concentration (Cmax) after at least about 1 hour of administration of the dosage form,. The present invention also provides process of preparing such dosage form compositions and prophylactic and / or therapeutic methods of using such dosage form.
Owner:PANACEA BIOTEC

Novel Pharmaceutical Modified Release Dosage Form Cyclooxygenase Enzyme Inhibitor

Pharmaceutical modified release dosage form comprising at least one cyclooxygenase enzyme inhibitor or its pharmaceutically acceptable salts, esters, prodrugs, solvates, hydrates, or derivatives thereof as active agent, with a pharmaceutically acceptable carrier for controlling the release of the cyclooxygenase enzyme inhibitor is provided. The dosage form preferably provides a release of not more than about 60% of the cyclooxygenase enzyme inhibitor in 1 hour and not less than about 75% of the cyclooxygenase enzyme inhibitor after 12 hours when tested in accordance with the dissolution method (I) described herein employing Distilled water with 2.0% Sodium lauryl sulphate as the dissolution medium or in accordance with the dissolution method (II) described herein employing pH 7.0 Phosphate buffer with 2.0% Sodium lauryl sulphate as the dissolution medium or in accordance with the dissolution method (III) described herein employing 0.001 N Hydrochloric acid with 1.0% Sodium lauryl sulphate as dissolution medium. Further, the pharmaceutical composition of the present invention when tested in a group of healthy humans preferably achieves a mean peak plasma concentration (Cmax) after at least about 1 hour of administration of the dosage form. The present invention also provides process of preparing such dosage form compositions and prophylactic and/or therapeutic methods of using such dosage form.
Owner:PANACEA BIOTEC

Externally applied emplastrum for treating anxious chronic bronchitis and preparation method thereof

The invention relates to an externally applied emplastrum for treating anxious chronic bronchitis and a preparation method thereof and belongs to the technical field of externally applied medical emplastrum. The preparation method thereof comprises the following steps of: extracting the ephedra, asarum, pinellia ternate, rhizoma arisaematis, fructus gleditsiae, rhizoma dioscoreae nipponicae, grass leaf sweetflag rhizome, blackberry lily, scutellaria baicalensis and platycodon grandiflorum by refluxing ethanol, reducing pressure and recovering the ethanol, concentrating the extracted solution into extractum, mixing the extractum with the aqueous phase solution prepared from stearic acid, solid paraffin, wool oil and ethyl p-hydroxybenzoate and the oil phase solution prepared from glycerol, sodium lauryl sulphate and triethanolamine so as to form ointment, and then paving on a frame. The medicine can quickly permeate into pained part through the conduction of acupuncture point and meridians and collaterals and the percutaneous absorption, so as to get through the Ren and Du meridians, relieve cough and asthma and regulate qi-flowing for eliminating phlegm. The invention solves the problems that the western medicine cures the symptoms but not root causes by using, the treatment limitation is big, the orally-taken dosage for Chinese traditional treatment is big, the taking is inconvenient and the curative effect is slow. The emplastrum of the invention is convenient to use, has good curative effect, becomes effective quickly, is free from side effect and is fit for both children and adults.
Owner:杨福海
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