51 results about "Sodium lauryl sulphate" patented technology

Pharmaceutical modified release dosage form comprising at least one cyclooxygenase enzyme inhibitor or its pharmaceutically acceptable salts, esters, prodrugs, solvates, hydrates, or derivatives thereof as active agent, with a pharmaceutically acceptable carrier for controlling the release of the cyclooxygenase enzyme inhibitor is provided. The dosage form preferably provides a release of not more than about 60 % of the cyclooxygenase enzyme inhibitor in 1 hour and not less than about 75 % of the cyclooxygenase enzyme inhibitor after 12 hours when tested in accordance with the dissolution method (I) described herein employing Distilled water with 2.0 % Sodium lauryl sulphate as the dissolution medium or in accordance with the dissolution method (II) described herein employing pH 7.0 Phosphate buffer with 2.0% Sodium lauryl sulphate as the dissolution medium or in accordance with the dissolution method (III) described herein employing 0.001 N Hydrochloric acid with 1.0 % Sodium lauryl sulphate as dissolution medium. Further, the pharmaceutical composition of the present invention when tested in a group of healthy humans preferably achieves a mean peak plasma concentration (Cmax) after at least about 1 hour of administration of the dosage form,. The present invention also provides process of preparing such dosage form compositions and prophylactic and / or therapeutic methods of using such dosage form.

The invention relates to an externally applied emplastrum for treating anxious chronic bronchitis and a preparation method thereof and belongs to the technical field of externally applied medical emplastrum. The preparation method thereof comprises the following steps of: extracting the ephedra, asarum, pinellia ternate, rhizoma arisaematis, fructus gleditsiae, rhizoma dioscoreae nipponicae, grass leaf sweetflag rhizome, blackberry lily, scutellaria baicalensis and platycodon grandiflorum by refluxing ethanol, reducing pressure and recovering the ethanol, concentrating the extracted solution into extractum, mixing the extractum with the aqueous phase solution prepared from stearic acid, solid paraffin, wool oil and ethyl p-hydroxybenzoate and the oil phase solution prepared from glycerol, sodium lauryl sulphate and triethanolamine so as to form ointment, and then paving on a frame. The medicine can quickly permeate into pained part through the conduction of acupuncture point and meridians and collaterals and the percutaneous absorption, so as to get through the Ren and Du meridians, relieve cough and asthma and regulate qi-flowing for eliminating phlegm. The invention solves the problems that the western medicine cures the symptoms but not root causes by using, the treatment limitation is big, the orally-taken dosage for Chinese traditional treatment is big, the taking is inconvenient and the curative effect is slow. The emplastrum of the invention is convenient to use, has good curative effect, becomes effective quickly, is free from side effect and is fit for both children and adults.