Golden buckwheat rhizome extract, pharmaceutical preparation containing golden buckwheat rhizome extract and preparation method thereof

Abstract

The invention relates to golden buckwheat rhizome extract and a pharmaceutical preparation containing same. The golden buckwheat rhizome extract is prepared through the following methods: golden buckwheat rhizome is taken, pulverized and then is extracted by circulated ethanol for four times, mass of each extraction solvent is respectively 6 times, 4 times, 3 times and twice of that of the golden buckwheat rhizome particles, extraction time is sequentially 90 minutes, 60 minutes, 60 minutes and 30 minutes, extracted liquid is combined and filtered, and the filtered liquid is decompressed and concentrated; water which is 20 times of the plaster is added to immerse the plaster to be mixed and suspended and then to be statically placed for one night; the upper clear liquid is chromatographically separated by macroporous adsorbent resin after being filtered; then the liquid is washed by water until the outflow liquid is colorless, then the liquid is eluted by 80% ethanol until the elution liquid is free from being reacted with ferric trichloride test solution, the elution liquid is collected, decompressed and concentrated and then is dried in an atomizing way, so the golden buckwheat rhizome extract is obtained. The golden buckwheat rhizome extract has higher content of active ingredients, the preparation has better characteristics, and the drug action is better.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a golden buckwheat extract, its preparation and a preparation method thereof. Background technique [0002] Tumor is a new organism formed by the body under the action of various carcinogenic factors, a certain cell in the local tissue loses its normal regulation of its growth at the gene level, resulting in abnormal clonal proliferation. It is generally believed that tumor cells are monoclonal, that is, all tumor cells in a tumor are descendants of a mutant cell. Tumors are generally divided into benign and malignant. All malignant tumors are collectively called cancer. [0003] Malignant tumors are major diseases that seriously threaten human survival and social development, and are one of the most serious public health problems in China and the world in the 21st century. For a long time, the prevalence of malignant tumors in my country is mostly described by death...

AI Technical Summary

Problems solved by technology

[0006] The existing dosage form on the market is a capsule prepared by the above method, but due to the hygroscopicity of the golden buckwheat extract, the condensed tannin contained in it is easy to precipitate with the gelatin in the capsule shell, and its disintegration time limit is often placed within one and a half years When it is close to or more than 30 minutes, it largely determines the difficulty of forming the preparation and the curative effect of the golden buckwheat extract capsule

Images