Panax notoginseng saponins freeze-dried powder injection and preparation method thereof
A technology of Panax notoginseng saponins and freeze-dried powder injection, which is applied in freeze-drying transportation, powder transportation, pharmaceutical formulation and other directions, can solve the problems of long turnaround time, no freezing method and conditions, and high production energy consumption. Efficiency improvement, significant economic and social benefits, energy saving effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0068] Example 1: Freeze-dried powder injection of Panax notoginseng saponins in 150mg loading capacity
[0069] Method: Dissolve Panax notoginseng saponins with water for injection, so that the concentration of Panax notoginseng saponins in the solution is 15.0% (g / ml), then subpackage according to 150mg filling volume, fill each bottle with 1ml, and put it in a freeze dryer:
[0070] 1) Pre-freezing and heat balance: start the compressor, set the temperature in the freeze dryer to -10°C within 0.75 hours, and maintain it for 0.5 hours;
[0071] 2) Freezing and system balance: After the end of heat release, set the temperature in the freeze dryer to drop below -30°C within 0.75 hours, and drop the temperature inside the freeze dryer to -30°C within 0.5 hours. Below 45°C; control the internal pressure of the freeze dryer to below 10Pa and maintain it for 1.5h;
[0072] 3) In the early stage of sublimation: set the temperature inside the freeze dryer to -4°C, and keep the vacu...
Embodiment 2
[0077] Example 2: 100 mg loading capacity of Panax notoginseng freeze-dried powder injection
[0078] Method: Dissolve Panax notoginseng saponins with water for injection, so that the concentration of Panax notoginseng saponins in the solution is 10.0% (g / ml), divide into 100mg filling volume, fill 1ml in each bottle, and place in a freeze dryer.
[0079] 1) Pre-freezing and heat balance: Start the compressor, set it within 0.25h to drop the temperature inside the freeze dryer to -10°C, and maintain it for 0.25h;
[0080] 2) Freezing and system balance: After the end of heat release, set the temperature in the freeze dryer to drop below -30°C within 0.25 hours, and after the temperature reaches -30°C, drop the temperature inside the freeze dryer to -45°C within 0.25 hours Below ℃; control the freeze dryer to below 10Pa and maintain it for 0.5h;
[0081] 3) In the early stage of sublimation: set the temperature inside the freeze dryer to -4°C, and keep the vacuum below 10Pa, a...
Embodiment 3
[0086] Example 3: 150 mg loading of total saponins of Panax notoginseng freeze-dried powder injection
[0087] Method: Dissolve Panax notoginseng saponins with water for injection, so that the concentration of Panax notoginseng saponins in the solution is 15.0% (g / ml), divide into 150 mg, fill each bottle with 1 ml, and place in a freeze dryer.
[0088] 1) Pre-freezing and heat balance: Start the compressor, set the temperature in the freeze dryer to drop to -10°C within 1 hour, and maintain it for 0.75 hours;
[0089] 2) Freezing and system balance: After the end of heat release, set the temperature in the freeze dryer to drop below -30°C within 1 hour, and after the temperature reaches -30°C, lower the temperature inside the freeze dryer to -45°C within 0.75 hours Below; control the pressure in the freeze dryer to below 10Pa and maintain it for 1h;
[0090] 3) In the early stage of sublimation: set the temperature inside the freeze dryer to -4°C, and keep the vacuum below 1...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com