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48results about How to "Short reconstitution time" patented technology

Ertapenem sodium for injection applicable to children's dose and its preparation method

PendingCN122537314Aprevent collapseshort reconstitution time
This invention belongs to the field of pharmaceutical formulation technology, specifically relating to an injectable ertapenem sodium suitable for pediatric dosage and its preparation method. Each vial contains 500 mg of ertapenem, and the injectable ertapenem sodium is prepared by lyophilization of the following components: 500 mg-530 mg ertapenem sodium; 150-300 mg mannitol; 100-180 mg trehalose dihydrate; 45-60 mg sodium bicarbonate; pH adjusted to 6.8-8.0 with sodium hydroxide; and water for injection added to a filling volume of 2.5 mL per vial. This invention provides a pediatric-specific specification, making clinical use more convenient, while also exhibiting excellent stability and suitability for industrial production.
Owner:GUANG DONG WAN TAI KE CHUANG YAO YE YOU XIAN GONG SI

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