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Preparation method for instant oviductus ranae particle

A technology of wood frog oil and granules, which is applied in the field of medicine and health products, can solve the problems of low utilization and absorption rate, and achieve the effects of improving absorption rate, rapid onset of effect, and stable process conditions

Active Publication Date: 2012-08-08
JILIN HUAKANG SHIYUAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Because Rana oil is insoluble in water, the traditional eating method needs to be soaked for a long time. It takes a long time to develop the dried Rana oil product to a practical state, and the utilization and absorption rate is low. How to improve Rana oil and ginseng The compatibility utilization efficiency has become a direction of current research and development

Method used

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  • Preparation method for instant oviductus ranae particle
  • Preparation method for instant oviductus ranae particle
  • Preparation method for instant oviductus ranae particle

Examples

Experimental program
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Effect test

Embodiment 1

[0070] Embodiment 1: the preparation of granule

[0071] Ginseng 1600g Rana Oil 1800g

[0072] Reflux extract ginseng with 60% ethanol three times, each time for 2 hours, add alcohol 10 times the amount of crude drug, filter, combine the filtrate, recover ethanol, concentrate to a thick paste with a relative density of 1.10-1.20 (measured at 60°C) , add water to make the alcohol content 30%, let it stand for 24 hours, recover ethanol, concentrate to a thick paste with a relative density of 1.12-1.32 (measured at 60°C), spray dry, pulverize into fine powder, remove tendons from Rana oil After filming, it is ultrafinely pulverized under the power of 20HZ into a superfine pulverized powder with a particle size of up to 0.3 microns, and the ginseng extract (component A contains 15%) and Rana oil superfine pulverized powder (component B contains 75%) , appropriate amount of skimmed milk powder, stevia sugar, milk essence, mix well, add 60% ethanol, the amount of alcohol added is 5...

Embodiment 2

[0073] Embodiment 2: the preparation of granule

[0074] Ginseng 1600g Rana Oil 1800g

[0075] Reflux extract ginseng with 80% ethanol three times, each time for 3 hours, the amount of alcohol added is 6 times the amount of crude drug, filter, combine the filtrate, recover ethanol, concentrate to a thick paste with a relative density of 1.10-1.20 (measured at 60°C) , add water to make the alcohol content 50%, let it stand for 48 hours, recover ethanol, concentrate to a thick paste with a relative density of 1.12-1.32 (measured at 60°C), dry it in vacuum at 60°C, crush it into fine powder, Rana oil After removing fascia and membranes, ultrafinely pulverize into ultrafine pulverized powder with a particle size of 0.3 microns under 45HZ power, take ginseng extract (component A contains 5%), wood frog oil superfine pulverized powder (component B contains 90%), appropriate amount of skimmed milk powder, stevioside, and milk essence, mix evenly, add 80% ethanol, the amount of alcoh...

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Abstract

The invention discloses a preparation method for an instant oviductus ranae particle. The preparation method is characterized by comprising the following steps of: A, preparing ginseng extract fine powder: performing reflux extraction on ginseng by using ethanol for three times, combining filtrates, recovering ethanol, concentrating into thick paste, adding water and alcohol for depositing, concentrating a supernatant into thick paste, and drying to obtain ginseng extract fine powder; B, preparing oviductus ranae submicron powder: removing tendons and membranes from oviductus ranae, drying, and smashing into a nanometer grade particle to obtain the oviductus ranae submicron powder; and C, forming particle: uniformly mixing the ginseng extract fine powder, the oviductus ranae submicron powder and other pharmaceutically-acceptable carriers, adding ethanol for pelletizing, drying, and pelletizing to obtain a finished product. In the method, Jilin ginseng is preferable. Due to the adoption of the preparation method, the product has the advantages of remarkable increase in the dissolution rate, increase in nutrient absorbing rate of a human body, quick response, high bioavailability, easiness for operating a process, no need of special equipment or chemical reagent, safe production, basic and stable process conditions, solving of 'three wastes' treatment problem, and suitability for industrial mass production.

Description

Technical field: [0001] The invention relates to the technical field of medicine and health products, in particular to a preparation method of instant Rana oil granules. technical background: [0002] Rana chinensis is a precious frog species that is famous for its medicinal, edible and health-care properties in my country. It inhabits the forests and swamps in the Northeast, where it lives in the spring breeze and sleeps with the winter snow. It is cold-resistant by nature, so it is also called snow frog. The reason why the Chinese forest frog is so precious is that this peculiar frog has strict requirements on the living environment. It must thrive in a natural environment with four distinct seasons and no pollution. It can be said that the unique natural environment in Northeast China has created this pure natural green medicinal resource of Chinese Rana. [0003] Studies have shown that ginseng has a good effect on preventing epidemic diseases, and has more healing fun...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/16A61P37/04A61P39/00A61K35/56A61K35/65
Inventor 胡军会张旭姜志刚刘会梅崔旭光
Owner JILIN HUAKANG SHIYUAN BIOTECH
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