OCT (optical coherence tomography)-based high-sensitivity measurement system and method with large dynamic range of flow speed

A high-sensitivity measurement and large dynamic range technology, applied in the field of high-sensitivity measurement systems, can solve problems such as limiting the dynamic range, and achieve the effects of suppressing phase noise, suppressing multiple scattering, and improving imaging quality

Active Publication Date: 2013-11-20
ZHEJIANG UNIV
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Problems solved by technology

Therefore, there is a trade-off problem in the detection of large and small flow rates, which limits the dynamic range of the system's flow rate measurement.

Method used

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  • OCT (optical coherence tomography)-based high-sensitivity measurement system and method with large dynamic range of flow speed
  • OCT (optical coherence tomography)-based high-sensitivity measurement system and method with large dynamic range of flow speed
  • OCT (optical coherence tomography)-based high-sensitivity measurement system and method with large dynamic range of flow speed

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Embodiment Construction

[0027] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0028] like figure 1 As shown, an OCT-based high-sensitivity measurement system for large dynamic range flow velocity in the present invention includes a broadband light source 1, a broadband fiber coupler 2, a sample arm, a reference arm and a detection arm. The sample arm includes a sample arm collimating mirror 3, a sample arm fast axis scanning galvanometer 4, a sample arm slow axis scanning galvanometer 5, a sample arm focusing lens 6 and a sample 7; the reference arm includes a reference arm collimating mirror 8. A reference arm focusing lens 9 and a reference arm plane mirror 10 , the detection arm includes a spectrometer collimating mirror 11 , a spectrometer blazed grating 12 , a spectrometer focusing lens 13 and a high-speed CMOS camera 14 . The broadband light source 1 is connected to one end of the broadband fiber coupler 2; the other end o...

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Abstract

The invention discloses an OCT (optical coherence tomography)-based high-sensitivity measurement system and method with a large dynamic range of flow speed. According to the measurement system and method disclosed by the invention, a two-dimensional scanning strategy combining fast scanning driven by saw-tooth waves and slow-speed scanning driven by step waves is adopted, and a high-speed CMOS (complementary metal oxide semiconductor) camera is utilized for acquiring an interference spectrum. A traditional phase resolution algorithm is adopted in the fast scanning direction for extracting high-flow-speed information, and a high-order correlation phase resolution algorithm is adopted in the slow-speed scanning direction for extracting slow-flow-speed information and a phase variance value corresponding to the large dynamic rate of the flow speed. A flow speed image is synthesized from the high-flow-speed information and the slow-flow-speed information. After space filtering and binarization are performed on a phase variance image, a mask image is obtained, and the flow speed image is processed by the mask image to get the final flow speed image. According to the measurement system and method disclosed by the invention, the dynamic range of measurement flow speed can be expanded, and the noise-limited speed detection sensitivity is further broken through.

Description

technical field [0001] The present invention relates to optical coherence tomography (OCT) technology and spectral domain optical coherence tomography (SD-OCT) technology, in particular to an OCT-based high-sensitivity measurement system and method for large dynamic range flow velocity. technical background [0002] Optical coherence tomography (OCT) imaging technology is a new type of optical imaging technology that can perform non-invasive, non-contact, high-resolution in vivo imaging of tissue structure and physiological functions. The field of non-destructive testing has broad application prospects. [0003] In order to obtain the functional information of the tissue, various functional OCTs have been developed one after another. Among them, Doppler OCT can realize the imaging of blood flow velocity, which is of great significance in medical research and clinical application. Most current flow velocity measurements are based on the traditional phase-resolved method, wh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00A61B5/026
Inventor 丁志华颜扬治黄良敏王川洪威沈毅卢锡清
Owner ZHEJIANG UNIV
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