Compound preparation for treating chronic obstructive pulmonary disease

A technology of chronic obstructive and compound preparations, applied in the field of medicine, can solve the problems of fixed airway obstruction and airway stenosis, achieve the effects of improving hypoxia, promoting sputum discharge, and increasing the body's antioxidant effect

Inactive Publication Date: 2012-09-19
HAINAN WEI KANG PHARMA QIANSHAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Airway wall structural remodeling, increased collagen content, and scar tissue formation occur during the repair process, which narrows the airway and causes fixed airway obstruction

Method used

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  • Compound preparation for treating chronic obstructive pulmonary disease
  • Compound preparation for treating chronic obstructive pulmonary disease
  • Compound preparation for treating chronic obstructive pulmonary disease

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Embodiment Construction

[0017] In order to make the technical means, creative features, goals and effects achieved by the present invention easy to understand, the present invention will be further described below in conjunction with specific embodiments.

[0018] A compound preparation for treating chronic obstructive pulmonary disease, the compound preparation contains ambroxol hydrochloride and 99.9%-0.1% scopolamine in a mass percentage of 0.1%-99.9%, and the compound preparation is prepared into injections and tablets , capsules, oral liquids, granules or syrups.

[0019] (1) According to FEV1 / FVC, FEV1% predicted value and clinical manifestations, the severity of COPD can be graded clinically (Table 1).

[0020] Table 1 Classification of clinical severity of COPD

[0021]

[0022] (2) Stages of COPD course.

[0023] 1. Stable period: The patient's symptoms such as cough, sputum, and shortness of breath are stable or mild.

[0024] 2. Acute exacerbation period: During the course of the dis...

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Abstract

The invention relates to a compound preparation for treating chronic obstructive pulmonary disease, relating to the medicine field; the compound preparation contains two components of ambroxol hydrochloride and scopolamine; mass percent of each component is as follows: the ambroxol hydrochloride has a mass percent of 0.1-99.9%, and the scopolamine has the mass percent of 99.9-0.1%; the compound preparation is prepared into injection, tablet, capsule, oral liquid, granules and syrup. The compound preparation provided by the invention has the advantages of reducing viscosity of sputum, enabling sputum to be thin, promoting sputum to exhaust, and improving self-purification of respiratory tract; 2) improving anti-oxidation effect of human body to be beneficial to enhancing own immunity of patients suffering from COPD (chronic obstructive pulmonary disease); 3) exciting respiratory centre, relieving smooth muscle spasm of bronchi and vessel, and reducing front and back load of heart to be beneficial to recovering cardiac function, also relieving microscopic artery spasm of organizations such as heart, brain, lung, kidney and so on, improving anaerobic condition of microcirculation and histiocyte, and improving clear function of epithelial surface of airway, thereby preventing and treating COPD.

Description

Technical field: [0001] The invention relates to the field of medicine, in particular to a compound preparation for treating chronic obstructive pulmonary disease. Background technique: [0002] Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease characterized by airflow limitation, which is not fully reversible and develops progressively. COPD mainly involves the lungs, but it can also cause systemic (or extrapulmonary) adverse effects. COPD is a common disease of the respiratory tract. As the age increases, the airway cilia clearance function of the elderly decreases, and the antioxidant effect of the lungs decreases. The elderly are prone to COPD. [0003] Chronic irritants such as tobacco smoke act on the lungs, causing abnormal inflammation in the lungs. COPD can involve the airway, lung parenchyma, and pulmonary vessels, manifested by a chronic inflammatory response dominated by infiltration of neutrophils, macrophages, and lymphocytes...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/46A61K31/137A61P11/00
Inventor 汪金灿汪六一
Owner HAINAN WEI KANG PHARMA QIANSHAN
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