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Preparation method of composite antibacterial surgical dressing

A compound antibacterial and production method technology, applied in the field of medical materials, can solve the problems of poor water absorption, induced infection, etc., and achieve the effect of enhanced antibacterial strength, no drug resistance, and accelerated wound healing

Inactive Publication Date: 2012-09-26
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chitosan / nano-silver composite film has poor water absorption performance, and it is easy to cause wound area fluid and induce infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Weigh 4 g of carboxymethyl chitosan and put it into a specific container, add distilled water up to 100 ml, put it into a stirrer and stir continuously for 6 hours to form a chitosan solution with a mass fraction of 4%. The chitosan solution was placed in an oven at 60°C and baked continuously for 40 hours to prepare a pure chitosan film, marked as CS.

Embodiment 2

[0019] Weigh 4 g of carboxymethyl chitosan and put it into a specific container, add distilled water up to 100 ml, put it into a stirrer and stir continuously for 6 hours to form a chitosan solution with a mass fraction of 4%. Weigh 2.0g of nano-silver powder and add it to the chitosan solution, continue to stir for 24 hours to make a uniform nano-silver / chitosan suspension, put the nano-silver / chitosan suspension into a 60°C oven for continuous Baking for 40 hours, the nano-silver / chitosan film was prepared, marked as N~CS 1 .

Embodiment 3

[0021] Weigh 4 g of carboxymethyl chitosan and put it into a specific container, add distilled water up to 100 ml, put it into a stirrer and stir continuously for 6 hours to form a chitosan solution with a mass fraction of 4%. Weigh 1.5g of nano-silver powder and add it to the chitosan solution, continue to stir for 24 hours to make a uniform nano-silver / chitosan suspension, put the nano-silver / chitosan suspension into a 60°C oven for continuous Baking for 40 hours, the nano-silver / chitosan film was prepared, marked as N~CS 2 .

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Abstract

The invention belongs to the field of medical materials and discloses a preparation method of a composite antibacterial surgical dressing. The preparation method comprises the following steps of: adding carboxymethyl chitosan into distilled water to prepare a solution; adding in nanometer silver powder to prepare a uniform nanometer silver / chitosan suspension, and placing the uniform nanometer silver / chitosan suspension into a 60-DEG C drying oven for continuous roasting to prepare a nanometer silver / chitosan film; mixing ES (Ethylene-Propylene Side by Side) short fiber and paper pulp, carrying out air forming at the temperature of 130 DEG C, adding in sodium polyacrylate, carrying out air forming again and spraying a structural adhesive, then, sticking non-woven fabrics to two sides and compacting the prepare a polymer absorbent material; and inlaying the nanometer silver / chitosan film on the polymer absorbent material, and then sticking the nanometer silver / chitosan film and the polymer absorbent material on a polyurethane film to prepare the composite antibacterial surgical dressing. The dressing provided by the invention is antibacterial by utilizing nanometer silver, chitosan can promote a wound to heal, and the polymer absorbent material can absorb redundant seepage of the wound, keep the wound wet and promote the wound to heal.

Description

[0001] technical field [0002] The invention relates to a method for making a composite antibacterial surgical dressing by combining a nano-silver / chitosan film and a polymer water-absorbing material, and belongs to the field of medical materials. technical background [0003] In the 1960s, Professor Winter discovered that when the wound surface is in a moist environment, it is more conducive to wound healing. At present, commonly used clinical dressings can be divided into dry dressings and wet dressings. Dry dressings, such as gauze and cotton pads, have a certain degree of water absorption, but are prone to wound adhesion and scab. The role of healing, the dressing loses its isolation effect after being soaked, and it is easy to cause wound infection. Although moist dressings such as hydrogel and chitosan dressings can keep the wound surface moist, their water absorption effect is not good, and it is easy to cause fluid accumulation and induce infection. In the past, s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/24A61L15/18A61L15/42
Inventor 漆白文周鹰飞喻爱喜
Owner WUHAN UNIV
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