Serologic biomarker miR-106b (microRNA) for detecting ovarian tumor and application thereof
A mir-106b, biomarker technology, applied in the field of biotechnology and medicine
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[0169] Example 1. Select 100 patients who have been diagnosed with malignant ovarian tumors (including 41 cases of serous adenocarcinoma, 32 cases of mucinous adenocarcinoma, 15 cases of endometrioid adenocarcinoma, and 12 cases of clear cell carcinoma), breast cancer patients, lung cancer patients 30 patients with stomach cancer, liver cancer, colon cancer, and prostate cancer, and 30 normal people. Peripheral blood was collected on an empty stomach in the early morning, and the entire detection method was the same as above. The results are shown in Table 8 below:
[0170] Table 8 Proportion of RQ>0.2 / ≤0.2 in different cancer cases
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[0173] From the data in the above table, it can be known that the proportion of RQ>0.2 in ovarian cancer is significantly higher than that of other cancers, that is, miR-106b is highly specific in ovarian cancer and can be used as an auxiliary treatment for individual ovarian tumors. The basis for screening, early detecti...
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