Non-contact photoacoustic and optical coherence tomography dual-imaging device and detection method thereof

An optical coherence tomography, non-contact technology, used in measurement devices, sonic diagnosis, infrasound diagnosis, etc., can solve the problems of irreconcilability, narrow frequency band, etc., and achieve the effects of easy movement, accurate information, and reasonable and effective system structure design.

Active Publication Date: 2013-02-27
SOUTH CHINA NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional photoacoustic signal detection tools are generally ultrasonic transducers, and photoacoustic signals have a wide frequency band, but traditional ultrasonic

Method used

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  • Non-contact photoacoustic and optical coherence tomography dual-imaging device and detection method thereof
  • Non-contact photoacoustic and optical coherence tomography dual-imaging device and detection method thereof
  • Non-contact photoacoustic and optical coherence tomography dual-imaging device and detection method thereof

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Embodiment 1

[0045] Such as figure 1 As shown, a non-contact photoacoustic and optical coherence tomography dual imaging device, including a signal detection component, a scanning delay line component, a scanning head component, a scanning head support component and a signal acquisition / processing component; a signal detection component, a scanning head component The scanning head support component is connected in sequence, the signal detection component is respectively connected with the scanning delay line component, the signal acquisition / processing component, and the scanning head component is connected with the signal acquisition / processing component;

[0046] The signal detection assembly includes a broadband light source 1-1, a fiber circulator 1-2, a fiber coupler 1-3, a fiber collimator A 1-4 and a photoelectric balance detector 1-5, a broadband light source 1-1, The fiber optic circulator 1-2, the fiber coupler 1-3 and the fiber collimator A 1-4 are connected sequentially, the ph...

Embodiment 2

[0062] The detection method using the non-contact photoacoustic and optical coherence tomography dual imaging device of embodiment 1 includes the following steps:

[0063] (1) After wiping the palm of the experimenter with 75% medical alcohol, apply 1mm of mineral oil, and fix it on the sample stage, and adjust the height;

[0064] (2) After the photoacoustic excitation light source and the broadband light source are combined into a beam of light through a dichroic mirror, it is irradiated onto the palm surface through a two-dimensional scanning galvanometer and a flat-field objective lens, and the positive lens group and one-dimensional translation stage are adjusted to make the photoacoustic excitation The light is focused on the surface of the palm, so that the photoacoustic signal detection light is focused on the surface of the oil layer;

[0065] (3) The photoacoustic excitation light is irradiated on the palm surface, and the photoacoustic signal is generated after the ...

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Abstract

The invention discloses a non-contact photoacoustic and optical coherence tomography dual-imaging device and a detection method thereof. The dual-imaging device comprises a signal detection assembly, a scanning delay line assembly, a scanning head assembly, a scanning head supporting assembly and a signal acquisition/processing assembly, wherein the signal detection assembly, the scanning head assembly and the scanning head supporting assembly are orderly connected with each other; the signal detection assembly is connected with the scanning delay line assembly and the signal acquisition/processing assembly, respectively; and the scanning head assembly and the signal acquisition/processing assembly are connected with each other. The non-contact photoacoustic and optical coherence tomography dual-imaging device is characterized in that the photoacoustic imaging device and the optical coherence tomography imaging device are organically combined with each other, the purpose of detecting the photoacoustic signal by detecting the vibration displacement on the biological tissue surface caused by the photoacoustic signal is achieved, the bandwidth limitation defect of the traditional transducer and the limitation on the detection of the coupled photoacoustic signal are avoided, and the respective imaging advantages of photoacoustic imaging and optical coherence tomography are complementary with each other; and the system is rational and effective in structural design and capable of providing more accurate information for clinical diagnosis.

Description

technical field [0001] The invention belongs to the technical field of photoacoustic imaging, in particular to a non-contact photoacoustic and optical coherence tomography dual imaging device and a detection method thereof. Background technique [0002] When a certain absorber is irradiated with light, the absorber absorbs the light energy and produces a temperature rise, and the temperature rise and fall causes the volume of the absorber to expand and shrink, and ultrasonic waves are generated. This phenomenon is called the photoacoustic effect. The photoacoustic effect has attracted people's attention since it was discovered in the 19th century, and it has been applied in various fields to varying degrees. As a new imaging technology, photoacoustic imaging has been applied in more and more fields. This imaging technology uses short-pulse laser as the excitation source, and the ultrasonic signal excited by it as the information carrier. By reconstructing the image of the c...

Claims

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Application Information

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IPC IPC(8): G01N21/17G01N21/45A61B19/00A61B5/00A61B8/00
Inventor 邢达陈重江杨思华
Owner SOUTH CHINA NORMAL UNIVERSITY
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