External patch for treating nocturnal enuresis and preparation method thereof

Abstract

The invention discloses an external patch for treating nocturnal enuresis and a preparation method thereof. The external patch comprises 15-25 parts of tenodera aridifolia stoll, 8-15 parts of cinnamon, 8-15 parts of fructus evodiae, 3-6 parts of platycodon grandiflorum and 3-6 parts of fructus alpiniae oxyphyllae. The method comprises the following steps of: weighing raw materials; adding water into the cinnamon and the fructus alpiniae oxyphyllae and distilling to extract volatile oil; covering by using beta-cyclodextrin; mixing the cinnamon and the fructus alpiniae oxyphyllae residues with the tenodera aridifolia stoll, the fructus evodiae and the platycodon grandiflorum; adding water to immerse and boiling; combining water decoctions and concentrating into an extract; mixing a volatile oil clathrate compound and the extract; heating and agitating until uniform dissolving and mixing, and then injecting into a mould; cooling and molding, and then de-molding; and placing a product into a non-woven rubberized fabric with an impermeable ring, and sealing and packaging to obtain a finished product. According to the external patch disclosed by the invention, biological activity of medicines and outer sensitive effects of meridians and acupuncture points are utilized to have the treating effect so as to effectively avoid a lot of untoward effects caused by oral taking; and the industrial batch production can be realized, the manufacturing cost is low, the curative effect is obvious, no toxic or side effect exists and the patient child compliance is better.

Description

technical field [0001] The invention relates to an external patch for treating enuresis in children and a preparation method thereof. Background technique [0002] Enuresis refers to a disease characterized by involuntary urination in children over 5 years old at night during sleep, not less than 2 times a week, and is characterized by waking up. According to some data, the incidence rate of enuresis in foreign children is 5% to 15%, and the survey of domestic children shows that the incidence rate is 5% to 12%. It can be seen that enuresis is a common clinical disease in pediatrics. The course of the disease is long, and it is easy to recur. In severe cases, enuresis will also occur during the day, which seriously affects the physical and mental health and growth and development of the children. [0003] In Western medicine, tricyclic antidepressants such as imipramine hydrochloride, meclofenate and desmopressin acetate are often used. Imipramine hydrochloride has not been...

AI Technical Summary

Problems solved by technology

[0003] In Western medicine, tricyclic antidepressants such as imipramine hydrochloride, meclofenate and desmopressin acetate are often used. Imipramine hydrochloride has not been used for the treatment of enuresis in children due to serious adverse reactions; There are few relevant research data on esters, and in-depth research is needed to explore its clinical effects; although desmopressin acetate has a certain curative effect, it is expensive and not accepted by the majority of patients, and the long-term curative effect is not stable after stopping the drug. , and desmopressin acetate is used in simple bedwetting patients, because some indications are difficult to grasp, there is still a certain risk