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Medicament for treating face acne

A facial acne and drug technology, applied in the directions of drug combination, pharmaceutical formula, hydroxyl compound active ingredients, etc., can solve the problems of side effects, worrying safety, one-sided treatment, etc. The effect of a significant therapeutic effect

Active Publication Date: 2013-06-05
兰州和盛堂制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, the safety of topical administration of retinoic acid to animals is worrying
[0005] 3. However, the above method has one-sided problems in treatment and has side effects

Method used

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  • Medicament for treating face acne

Examples

Experimental program
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Effect test

Embodiment Construction

[0046] Weigh according to the weight ratio of raw materials:

[0047] Metronidazole 30g Chloramphenicol 10g Borneol 1g

[0048] Sublimated sulfur 60g Stearic acid 200g Glyceryl monostearate 40g

[0049] Lecithin 10g Propylene Glycol 100g Triethanolamine 25g

[0050] twain -80 Add 25g purified water to 1000g

[0051] The preparation method is:

[0052] ①Oil phase: Take 200g of stearic acid, 40g of glyceryl monostearate, and 10g of lecithin, pour them into an oil ointment tank, place them in a water bath and heat to 70 o C, mix and melt for later use;

[0053] ②Water phase: Dissolve 30g of metronidazole and 10g of chloramphenicol in an appropriate amount of purified water, and add 100g of propylene glycol, 25g of triethanolamine, Tween -80 25g, 50 o C is heated until dissolved, mixed well, and set aside;

[0054] ③ Grind sublimated sulfur 60g finely, pass through an 80-mesh sieve, and set aside;

[0055] ④ Grind 1g of borneol finely, pass it through an 80-mesh sieve, a...

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Abstract

The invention relates to a medicament for treating face acne, and particularly relates to a 'Miancuojing ointment' for treating acne diseases such as comedo, seborrheic dermatitis, rosacea, and the like. The medicament is prepared from metronidazole, chloramphenicol, borneol, sublimed sulfur, stearic acid, glycerin monostearate, lecithin, propylene glycol, triethanolamine, tween, distilled water and the like through process steps; the medicament of the invention has the effects of resisting propionibacterium acnes, dissolving skin cutin, and reducing skin free lipid, and has significant curative effects on acne (comedo), seborrheic dermatitis, and rosacea.

Description

technical field [0001] The invention relates to a medicine for treating facial acne, in particular to a "face acne cleansing ointment" for treating acne, seborrheic dermatitis, rosacea and other acne diseases. Background technique [0002] Acne is a chronic inflammatory skin disease of the pilosebaceous glands caused by various factors. The current treatment methods for acne include: [0003] 1. The medicines taken orally are mainly antibiotics, mainly antibacterial and anti-inflammatory, but some medicines contain tetracycline. If taken for a long time, it will virtually increase the burden on the liver and kidneys, especially contraindicated for pregnant women. [0004] 2. Retinoic acid drug treatment is due to differences in skin structure and sensitivity to retinoic acid stimulation between animals and humans. Therefore, the safety of topical administration of retinoic acid to animals is worrying. [0005] 3. But the above-mentioned method has the problem of one-sided...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/04A61P17/10A61K31/045A61K31/047A61K31/133A61K31/165A61K31/20A61K31/22A61K31/4164A61K31/685
Inventor 张文龙郭玉华宋风莉
Owner 兰州和盛堂制药股份有限公司
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